Rome2Rio

How to get fromSiena to Sicilyby train, plane, car, car ferry, train (Trenitalia), or bus

Find Transport to Sicily

See all options

There are 13 ways to get from Siena to Sicily by train, plane, car, car ferry, train (Trenitalia), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    5h 3m
    €53–195

  2. Train, train to Pisa International Airport, fly to Palermo Airport

    cheapest
    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    5h 18m
    €49–217

  3. Drive, car ferry

    1. Drive from Siena to Civitavecchia Portcar car
    2. Take the car ferry from Civitavecchia Port to Palermo Portocarferry car ferry
    15h 44m
    €84–127

  4. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    16h 28m
    €131–291

  5. Bus

    1. Take the bus from Siena to Palermobus bus N597
    16h 33m
    €102–166

  6. Train to Florence Peretola Airport, fly to Palermo Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane plane FLR - PMO
    5h 24m
    €77–198

  7. Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    5h 2m
    €57–184

  8. Train, train to Pisa International Airport, fly to Trapani Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane plane PSA - TPS
    6h
    €56–163

  9. Train, train to Fiumicino International Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane plane FCO - CTA
    6h 27m
    €72–220

  10. Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane plane PEG - PMO
    6h 20m
    €64–225

  11. Train, train to Fiumicino International Airport, fly to Vincenzo Magliocco Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Vincenzo Magliocco Airport (CIY)plane plane FCO - CIY
    6h 25m
    €104–282

  12. Train via Chiusi (Trenitalia)

    1. Take the train from Siena to Chiusi-Chianciano T.train train Re
    2. Take the train from Chiusi-Chianciano T. to Roma Terminitrain train Re
    3. Take the train from Roma Termini to Palermo Centraletrain train Ic
    17h 17m
    €118–245

  13. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus bus
    23h 5m

Siena to Sicily by train (Trenitalia)

Calendar14Weekly Trains
Duration16h 28mAverage Duration
Ticket€131Cheapest Price
See schedules

Questions & Answers

Map of how to get from Siena to Sicily.ExpandLaunch map view
  • Distance: 877.7 km
  • Duration: 5h 3m

What companies run services between Siena, Italy and Sicily, Italy?

You can take a train from Siena to Palermo Notarbartolo via Firenze S.M.N., Roma Termini, and Palermo Centrale in around 16h 28m. Alternatively, FlixBus operates a bus from Siena to Palermo once daily. Tickets cost €100–170 and the journey takes 16h.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers