There are 10 ways to get from Siena to Sicily by train, plane, car, car ferry, train (Trenitalia), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
4h 54m€43–202Drive, car ferry
- Drive from Siena to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
15h 44m€89–127Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
16h 16m€130–263Bus
- Take the bus from Siena to Palermobus N597
16h 31m€100–158Train to Florence Peretola Airport, fly to Palermo Airport
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane FLR - PMO
5h 15m€76–214Train, train to Pisa International Airport, fly to Palermo Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane PSA - PMO
5h 18m€56–253Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
5h 2m€57–231Train, train to Pisa International Airport, fly to Trapani Airport
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Trapani Airport (TPS)plane PSA - TPS
6h€61–320Train via Chiusi (Trenitalia)
- Take the train from Siena to Chiusi-Chianciano T.train Re
- Take the train from Chiusi-Chianciano T. to Roma Terminitrain Re
- Take the train from Roma Termini to Palermo Centraletrain Ic
17h 1m€118–228Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Palermo Piazza Cairolibus
22h 56m€199–280
Siena to Sicily by train (Trenitalia)
Questions & Answers
The cheapest way to get from Siena to Sicily is to train and fly which costs €40 - €210 and takes 4h 54m.
The fastest way to get from Siena to Sicily is to train and fly which takes 4h 54m and costs €40 - €210.
No, there is no direct bus from Siena to Sicily. However, there are services departing from Siena and arriving at Piazza Boiardo via Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 16h 31m.
No, there is no direct train from Siena to Sicily. However, there are services departing from Siena and arriving at Palermo Notarbartolo via Firenze S.M.N., Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 16h 16m.
The distance between Siena and Sicily is 878 km.
The best way to get from Siena to Sicily without a car is to train which takes 16h 16m and costs €130 - €270.
It takes approximately 4h 54m to get from Siena to Sicily, including transfers.
Siena to Sicily bus services, operated by FlixBus, depart from Siena station.
Siena to Sicily train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Sicily is to train which takes 16h 16m and costs €130 - €270. Alternatively, you can bus, which costs €100 - €160 and takes 16h 31m.
What companies run services between Siena, Italy and Sicily, Italy?
You can take a train from Siena to Palermo Notarbartolo via Firenze S.M.N., Roma Termini, and Palermo Centrale in around 16h 16m. Alternatively, FlixBus operates a bus from Siena to Palermo once daily. Tickets cost €95–160 and the journey takes 16h.
- Website
- ryanair.com
Flights from Pisa International Airport to Palermo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €30–190
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–190
Flights from Pisa International Airport to Trapani Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €40–230
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–17
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–9
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–9
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–9
- Website
- Trenitalia
Train from Siena to Chiusi-Chianciano T.
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €10–16
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Roma Termini
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €18–27
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Siena to Palermo
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- €95–160
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–85
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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More Questions & Answers
Siena to Sicily bus services, operated by FlixBus, arrive at Palermo station.
Siena to Sicily train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Sicily train tickets online with Omio.
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