There are 9 ways to get from Siena to Syracuse by train, plane, bus, ferry, night train, train (Trenitalia), car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly, bus
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 50m€58–199Train, train to Bologna Guglielmo Marconi Airport, fly, bus
cheapest- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane BLQ - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 29m€44–257Train, ferry
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Siracusatrain Re
13h 57mBus
- Take the bus from Siena to Cataniabus N597 / ...
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus Catania
14h 31m€66–151Train, night train
- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the night train from Firenze Campo Marte to Siracusanighttrain Ini
18h 21m€113–220Train, train to Pisa International Airport, fly, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 55m€57–188Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Siracusatrain Ic
15h 45m€125–274Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the bus from Florence Villa Constanza Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
19h 31m€76–157Drive, car ferry
- Drive from Siena to Villa S. Giovannicar
- Take the car ferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
10h 38m€182–273
Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA) flights
Questions & Answers
The cheapest way to get from Siena to Syracuse is to bus via Florence which costs €75 - €160 and takes 19h 31m.
The fastest way to get from Siena to Syracuse is to train and fly and bus which takes 5h 50m and costs €55 - €200.
No, there is no direct bus from Siena to Syracuse. However, there are services departing from Siena and arriving at Siracusa - Von Platen via Catania Via Archimede. The journey, including transfers, takes approximately 14h 31m.
No, there is no direct train from Siena to Syracuse. However, there are services departing from Siena and arriving at Siracusa via Firenze S.M.N. and Firenze Campo Marte. The journey, including transfers, takes approximately 18h 21m.
The distance between Siena and Syracuse is 932 km.
The best way to get from Siena to Syracuse without a car is to train and ferry which takes 13h 57m and costs .
It takes approximately 5h 50m to get from Siena to Syracuse, including transfers.
Siena to Syracuse bus services, operated by FlixBus, depart from Siena station.
Siena to Syracuse train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Syracuse is to bus which takes 14h 31m and costs €65 - €160. Alternatively, you can train, which costs €120 - €280 and takes 15h 45m.
What companies run services between Siena, Italy and Syracuse, Italy?
You can take a bus from Siena to Siracusa - Von Platen via Catania and Catania Via Archimede in around 14h 31m. Alternatively, you can take a train from Siena to Siracusa via Firenze S.M.N. and Roma Termini in around 15h 45m.
- Website
- ryanair.com
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–140
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday
- Estimated price
- €35–140
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €35–140
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–170
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Wednesday and Saturday
- Estimated price
- €40–170
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- €80–170
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €75–180
- Website
- volotea.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €27–150
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €80–170
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €75–180
- Website
- vueling.com
Flights from Florence Peretola Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Friday, and Sunday
- Estimated price
- €50–190
- Website
- flyulendo.com
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €17–80
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 45m
- Frequency
- Every 2 hours
- Estimated price
- €22–40
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 44 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 4h 6m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Napoli Afragola
- Ave. Duration
- 2h 48m
- Frequency
- Hourly
- Estimated price
- €70–140
- Schedules at
- trenitalia.com
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 4h
- Frequency
- Every 2 hours
- Estimated price
- €60–130
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 52m
- Frequency
- Every 15 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Napoli Afragola
- Ave. Duration
- 2h 44m
- Frequency
- 4 times a day
- Estimated price
- €60–120
- Website
- https://www.italotreno.it/en
Train from Napoli Afragola to Villa S.Giovanni
- Ave. Duration
- 5h 37m
- Frequency
- Once daily
- Estimated price
- €50–110
- Website
- https://www.italotreno.it/en
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- €19–40
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Siracusa
- Ave. Duration
- 11h 12m
- Frequency
- Twice daily
- Estimated price
- €85–180
- Website
- https://www.trenitalia.com/en.html
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Firenze Campo Marte to Siracusa
- Ave. Duration
- 15h 36m
- Frequency
- Twice daily
- Estimated price
- €100–200
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- [email protected]
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €4–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €4–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €4–9
- Schedules at
- interbus.it
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Siena to Catania
- Ave. Duration
- 12h 55m
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Catania
- Ave. Duration
- 14h 40m
- Frequency
- Once daily
- Estimated price
- €60–120
- Website
- https://www.itabus.it/en/home
Bus from Florence Villa Constanza Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 15h 25m
- Frequency
- Twice daily
- Estimated price
- €65–140
- Website
- https://www.itabus.it/en/home
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Travelling by boat in Italy
Read the travel guide
More Questions & Answers
Siena to Syracuse bus services, operated by FlixBus, arrive at Catania station.
Siena to Syracuse train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Syracuse train tickets online with Omio.
Book your Siena to Syracuse bus tickets online with Omio.
There are 3324+ hotels available in Syracuse.











































