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How to get fromSiena to Syracuseby train, plane, bus, train (Trenitalia), night train, car, or car ferry

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There are 9 ways to get from Siena to Syracuse by train, plane, bus, train (Trenitalia), night train, car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly, bus

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    5h 50m
    €38–205

  2. Bus

    1. Take the bus from Siena to Cataniabus bus N597 / ...
    2. Take the bus from Catania Via Archimede to Siracusa - Von Platenbus bus Catania
    14h 31m
    €55–132

  3. Train (Trenitalia)

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Siracusatrain train Ic
    15h 33m
    €123–240

  4. Train, night train

    1. Take the train from Siena to Firenze S.M.N.train train Re / ...
    2. Take the nighttrain from Firenze Campo Marte to Siracusanighttrain night train Ini
    18h 21m
    €107–176

  5. Train, train to Pisa International Airport, fly, bus

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    4. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    5h 57m
    €55–233

  6. Train, train to Bologna Guglielmo Marconi Airport, fly, bus

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane plane BLQ - CTA
    4. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    6h 31m
    €40–273

  7. Bus to Perugia Sant'Egidio Airport, fly, bus

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane plane PEG - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    6h 54m
    €58–285

  8. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence Villa Constanza Bus Station to Catania Fontanarossa Airport Bus Stopbus bus
    3. Take the bus from Catania Airport to Siracusa - Von Platenbus bus
    19h 31m
    €64–126

  9. Drive, car ferry

    1. Drive from Siena to Villa S. Giovannicar car
    2. Take the carferry from Villa S. Giovanni to Tresmestiericarferry car ferry
    3. Drive from Tresmestieri to Syracusecar car
    10h 38m
    €188–280

Siena to Syracuse by bus

Calendar21Weekly Buses
Duration14h 31mAverage Duration
Ticket€55Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Syracuse.ExpandLaunch map view
  • Distance: 932 km
  • Duration: 5h 50m

What companies run services between Siena, Italy and Syracuse, Italy?

You can take a bus from Siena to Siracusa - Von Platen via Catania and Catania Via Archimede in around 14h 31m. Alternatively, you can take a train from Siena to Siracusa via Firenze S.M.N. and Roma Termini in around 15h 33m.

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