There are 11 ways to get from Siena to Syracuse by train, plane, bus, ferry, night train, train (Trenitalia), car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly, bus
best- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane FLR - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 50m€38–205Train, ferry
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Siracusatrain Re
14hBus
- Take the bus from Siena to Cataniabus N597 / ...
- Take the bus from Catania Via Archimede to Siracusa - Von Platenbus Catania
14h 31m€55–134Train, night train
- Take the train from Siena to Firenze S.M.N.train Re / ...
- Take the nighttrain from Firenze Campo Marte to Siracusanighttrain Ini
18h 21m€107–176Train, train to Pisa International Airport, fly, bus
- Take the train from Siena to Empolitrain
- Take the train from Empoli to Pisa Centraletrain
- Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane PSA - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
5h 57m€55–233Train, train to Bologna Guglielmo Marconi Airport, fly, bus
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Catania–Fontanarossa Airport (CTA)plane BLQ - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 28m€40–273Bus to Perugia Sant'Egidio Airport, fly, bus
- Take the bus from Siena to Perugiabus
- Fly from Perugia Sant'Egidio Airport (PEG) to Catania–Fontanarossa Airport (CTA)plane PEG - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
6h 54m€58–285Train, train to Fiumicino International Airport, fly, bus
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Catania–Fontanarossa Airport (CTA)plane FCO - CTA
- Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus
7h 27m€67–204Train (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Siracusatrain Ic
15h 30m€124–240Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the bus from Florence Villa Constanza Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Take the bus from Catania Airport to Siracusa - Von Platenbus
19h 31m€64–116Drive, car ferry
- Drive from Siena to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Syracusecar
10h 38m€188–280
Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Siena to Syracuse is to bus via Florence which costs €60 - €120 and takes 19h 31m.
The fastest way to get from Siena to Syracuse is to train and fly and bus which takes 5h 50m and costs €35 - €210.
No, there is no direct bus from Siena to Syracuse. However, there are services departing from Siena and arriving at Siracusa - Von Platen via Catania Via Archimede. The journey, including transfers, takes approximately 14h 31m.
No, there is no direct train from Siena to Syracuse. However, there are services departing from Siena and arriving at Siracusa via Firenze S.M.N. and Firenze Campo Marte. The journey, including transfers, takes approximately 18h 21m.
The distance between Siena and Syracuse is 932 km.
The best way to get from Siena to Syracuse without a car is to train and ferry which takes 14h and costs .
It takes approximately 5h 50m to get from Siena to Syracuse, including transfers.
Siena to Syracuse bus services, operated by FlixBus, depart from Siena station.
Siena to Syracuse train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Syracuse is to bus which takes 14h 31m and costs €55 - €140. Alternatively, you can train, which costs €120 - €240 and takes 15h 30m.
What companies run services between Siena, Italy and Syracuse, Italy?
You can take a bus from Siena to Siracusa - Von Platen via Catania and Catania Via Archimede in around 14h 31m. Alternatively, you can take a train from Siena to Siracusa via Firenze S.M.N. and Roma Termini in around 15h 30m.
- Website
- ryanair.com
Flights from Pisa International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 25m
- When
- Thursday
- Estimated price
- €30–180
Flights from Pisa International Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- €30–180
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 47m
- When
- Tuesday and Thursday
- Estimated price
- €30–210
Flights from Bologna Guglielmo Marconi Airport to Catania–Fontanarossa Airport via Bari
- Ave. Duration
- 3h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–210
Flights from Perugia Sant'Egidio Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €45–230
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €22–80
Flights from Fiumicino International Airport to Catania–Fontanarossa Airport via Malta
- Ave. Duration
- 3h 20m
- When
- Monday
- Estimated price
- €22–80
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Messina Centrale to Siracusa
- Ave. Duration
- 2h 45m
- Frequency
- Every 2 hours
- Estimated price
- €21–29
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Via Archimede to Siracusa - Von Platen
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €3–9
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - v.le Scala Greca
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
Bus from Catania Airport to Siracusa - Von Platen
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €2–8
- Schedules at
- interbus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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Booking & Getting There
Siena to Syracuse bus services, operated by FlixBus, arrive at Catania station.
Siena to Syracuse train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Book your Siena to Syracuse train tickets online with Omio.
Book your Siena to Syracuse bus tickets online with Omio.
There are 3098+ hotels available in Syracuse.





