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How to get fromSiesta Key to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 6 ways to get from Siesta Key to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS)plane plane SRQ - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 17m
    $172–870

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Sarasota–Bradenton International Airport (SRQ) to Asheville Regional Airport (AVL)plane plane SRQ - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    5h 31m
    $100–486

  3. Bus, drive

    1. Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    22h 8m

  4. Drive, train, bus

    1. Drive from Siesta Key to Tampacar car
    2. Take the train from Tampa to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    25h 33m
    $303–615

  5. Drive 676.5 mi

    1. Drive from Siesta Key to Great Smoky Mountainscar car 676.5 mi
    12h 39m
    $124–179

  6. Bus, drive via University

    1. Take the bus from Bradenton/Sarasota - Mobil Gas Station to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    22h 52m

Sarasota–Bradenton International Airport (SRQ) to Mcghee Tyson Airport (TYS) flights

Calendar22Weekly Planes
Duration3h 17mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from Siesta Key to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 660.5 mi
  • Duration: 5h 17m

What companies run services between Siesta Key, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Siesta Key to Great Smoky Mountains. However, you can take the line 77 bus to Main St @ Lemon Ave, walk to Downtown Transfer Station, take the bus to Airport Cir @ Bradenton Connector Ns, walk to Sarasota–Bradenton International Airport (SRQ) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Ocean Blvd @ Avenida Madera NB to Great Smoky Mountains via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, Charlotte Bus Station, and Asheville, NC in around 22h 8m.

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