There are 6 ways to get from Siesta Key to Myrtle Beach by plane, car, train, bus, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Sarasota–Bradenton International Airport
best- Fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR)plane SRQ - MYR
5h 50m$112–568Drive 576.3 mi
cheapest- Drive from Siesta Key to Myrtle Beachcar 576.3 mi
10h 46m$106–152Drive, train, bus
- Drive from Siesta Key to Tampacar
- Take the train from Tampa to Kissimmee Amtrak Stationtrain
- Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
14h 54m$144–335Bus
- Take the bus from Sarasota Cattlemen Transfer Center to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
20h 18m$128–198Bus to Tampa, fly
- Take the bus from Sarasota Cattlemen Transfer Center to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
7h 13m$116–376Amtrak Thruway, train, bus
- Take the bus from Sarasota Amtrak Bus Stop to Orlando, FLbus
- Take the train from Orlando to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
17h 47m$148–318
Siesta Key to Myrtle Beach by bus
Comparing Your Travel Options
The cheapest way to get from Siesta Key to Myrtle Beach is to drive which costs $100 - $160 and takes 10h 46m.
The fastest way to get from Siesta Key to Myrtle Beach is to fly which takes 5h 50m and costs $110 - $600.
No, there is no direct bus from Siesta Key to Myrtle Beach station. However, there are services departing from Ocean Blvd @ Avenida Madera NB and arriving at Myrtle Beach Bus Station via Downtown Transfer Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station and Fayetteville Bus Station. The journey, including transfers, takes approximately 20h 18m.
The distance between Siesta Key and Myrtle Beach is 505 miles. The road distance is 579.6 miles.
The best way to get from Siesta Key to Myrtle Beach without a car is to bus which takes 20h 18m and costs $120 - $200.
It takes approximately 5h 50m to get from Siesta Key to Myrtle Beach, including transfers.
Siesta Key to Myrtle Beach bus services, operated by Flixbus USA, depart from Sarasota Cattlemen Transfer Center station.
The best way to get from Siesta Key to Myrtle Beach is to fly which takes 5h 50m and costs $110 - $600. Alternatively, you can bus, which costs $120 - $200 and takes 20h 18m.
Siesta Key to Myrtle Beach bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Siesta Key to Myrtle Beach is 580 miles. It takes approximately 10h 46m to drive from Siesta Key to Myrtle Beach.
What companies run services between Siesta Key, FL, USA and Myrtle Beach, SC, USA?
Delta, American Airlines, and Southwest Airlines fly from Sarasota–Bradenton International Airport (SRQ) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Ocean Blvd @ Avenida Madera NB to Myrtle Beach Bus Station via Main St @ Lemon Ave, Downtown Transfer Station, Cattlemen Transit Station, Sarasota Cattlemen Transfer Center, Orlando Bus Station, and Fayetteville Bus Station in around 20h 18m.
- Website
- delta.com
Flights from Sarasota–Bradenton International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $100–600
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $65–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Tampa to Kissimmee Amtrak Station
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $18–45
- Website
- Amtrak
Train from Kissimmee Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 8h 28m
- Frequency
- Once daily
- Estimated price
- $100–250
- Website
- Amtrak
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $95–240
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 5704+ hotels available in Myrtle Beach.





