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How to get fromSikeston to Biloxiby car, plane, train, taxi, or bus

Find Transport to Biloxi

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There are 6 ways to get from Sikeston to Biloxi by car, plane, train, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Sikeston to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Gulfport-Biloxi Regional Airport (GPT)plane plane PAH - GPT
    6h 52m
    $145–610

  2. Drive  508.3 mi

    cheapest
    1. Drive from Sikeston to Biloxicar car 508.3 mi
    8h 39m
    $93–134

  3. Drive, train (Amtrak)

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    15h 44m
    $343–538

  4. Taxi, bus, train

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    17h 33m
    $229–331

  5. Bus to Memphis, fly

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Fly from Memphis (MEM) to Gulfport-Biloxi Regional Airport (GPT)plane plane MEM - GPT
    9h 3m
    $215–759

  6. Taxi to Cape Girardeau Municipal Airport, fly

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Gulfport-Biloxi Regional Airport (GPT)plane plane CGI - GPT
    8h 29m
    $239–745

Barkley Regional Airport (PAH) to Gulfport-Biloxi Regional Airport (GPT) flights

Calendar7Weekly Planes
Duration5h 15mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sikeston to Biloxi.ExpandLaunch map view
  • Distance: 528.6 mi
  • Duration: 6h 52m

What companies run services between Sikeston, MO, USA and Biloxi, MS, USA?

There is no direct connection from Sikeston to Biloxi. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Gulfport-Biloxi Regional Airport (GPT), then take the taxi to Biloxi. Alternatively, you can take a vehicle from Sikeston to Biloxi Amtrak Sta via Fulton Amtrak Station and New Orleans Union Passenger Terminal in around 15h 44m.

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