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How to get fromSikeston to Charlestonby taxi, bus, plane, or car

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There are 5 ways to get from Sikeston to Charleston by taxi, bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus to Lambert–St. Louis International Airport, fly

    best
    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS)plane plane STL - CHS
    7h 37m
    $216–701

  2. Drive 727.7 mi

    cheapest
    1. Drive from Sikeston to Charlestoncar car 727.7 mi
    13h 5m
    $133–192

  3. Drive, bus

    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    22h 17m
    $146–271

  4. Bus to Memphis, fly

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Fly from Memphis (MEM) to Charleston International Airport (CHS)plane plane MEM - CHS
    10h 8m
    $191–696

  5. Taxi to Cape Girardeau Municipal Airport, fly

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Charleston International Airport (CHS)plane plane CGI - CHS
    8h 26m
    $186–592

Lambert–St. Louis International Airport (STL) to Charleston International Airport (CHS) flights

Calendar52Weekly Planes
Duration3h 48mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Charleston.ExpandLaunch map view
  • Distance: 880.3 mi
  • Duration: 7h 37m

What companies run services between Sikeston, MO, USA and Charleston, SC, USA?

There is no direct connection from Sikeston to Charleston. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a vehicle from Sikeston to Transit Mall via Paducah Bus Station, Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 22h 17m.

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