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How to get fromSikeston to Destinby taxi, plane, car, train, or bus

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There are 10 ways to get from Sikeston to Destin by taxi, plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Cape Girardeau Municipal Airport, fly to Pensacola International Airport, taxi

    best
    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS)plane plane CGI - PNS
    3. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    3h 36m
    $324–730

  2. Drive 597.7 mi

    cheapest
    1. Drive from Sikeston to Destincar car 597.7 mi
    10h 55m
    $110–158

  3. Drive, train, bus, taxi

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    20h 3m
    $339–588

  4. Taxi, bus, train

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Pascagoulatrain train
    4. Take the bus from Pascagoula to Crestviewbus bus
    5. Take the taxi from Crestview to Destintaxi taxi
    22h 21m
    $344–516

  5. Taxi, bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    6h 20m
    $239–674

  6. Taxi, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    6h 46m
    $242–592

  7. Drive, bus to Nashville, fly to Destin–Fort Walton Beach Airport

    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Destin–Fort Walton Beach Airport (VPS)plane plane BNA - VPS
    7h 18m
    $134–489

  8. Taxi, bus to Lambert–St. Louis International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    4. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    7h 3m
    $344–809

  9. Taxi, bus to Lambert–St. Louis International Airport, fly to Pensacola International Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    4. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    7h 12m
    $314–739

  10. Drive, bus to Nashville, fly to Northwest Florida Beaches International Airport, taxi

    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Northwest Florida Beaches International Airport (ECP)plane plane BNA - ECP
    4. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    7h 57m
    $234–614

Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS) flights

Calendar2Weekly Planes
Duration1h 45mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Destin.ExpandLaunch map view
  • Distance: 566.5 mi
  • Duration: 3h 36m

What companies run services between Sikeston, MO, USA and Destin, FL, USA?

There is no direct connection from Sikeston to Destin. However, you can take the taxi to Cape Girardeau Municipal Airport (CGI) airport, fly to Pensacola International Airport (PNS), then take the taxi to Destin. Alternatively, you can drive to Fulton Amtrak Station, take the train to New Orleans Union Passenger Terminal, take the train to Gulfport Amtrak Sta, walk to Gulfport, take the bus to Crestview, then take the taxi to Destin.

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