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How to get fromSikeston to Great Smoky Mountainsby taxi, plane, car, or bus

Find Transport to Great Smoky Mountains

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There are 5 ways to get from Sikeston to Great Smoky Mountains by taxi, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Cape Girardeau Municipal Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Mcghee Tyson Airport (TYS)plane plane CGI - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 47m
    $234–866

  2. Drive 426.1 mi

    cheapest
    1. Drive from Sikeston to Great Smoky Mountainscar car 426.1 mi
    8h 14m
    $78–113

  3. Drive, bus

    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    4. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    21h 1m
    $152–277

  4. Bus to Memphis, fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Fly from Memphis (MEM) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MEM - ATL
    3. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    10h 40m
    $464–1,059

  5. Bus, drive

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - Nashvillebus bus
    3. Take the bus from Omni Nashville Hotel to Grand Hyatt Atlanta in Buckheadbus bus
    4. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    5. Drive from Taqueria Guadalajara - Greenville to ART Stationcar car
    6. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    22h 17m
    $377–729

Cape Girardeau Municipal Airport (CGI) to Mcghee Tyson Airport (TYS) flights

Calendar13Weekly Planes
Duration6h 21mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 413.3 mi
  • Duration: 7h 47m

What companies run services between Sikeston, MO, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Sikeston to Great Smoky Mountains. However, you can take the taxi to Cape Girardeau Municipal Airport (CGI) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a vehicle from Sikeston to Great Smoky Mountains via Paducah Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 21h 1m.

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