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How to get fromSikeston to Indianapolisby taxi, bus, car, train, plane, or bus (Greyhound)

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There are 7 ways to get from Sikeston to Indianapolis by taxi, bus, car, train, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus (Greyhound)

    best
    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    7h 50m
    $147–221

  2. Drive 327.1 mi

    cheapest
    1. Drive from Sikeston to Indianapoliscar car 327.1 mi
    5h 25m
    $60–87

  3. Drive, train, bus

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    9h 49m
    $122–248

  4. Drive to Barkley Regional Airport, fly

    1. Drive from Sikeston to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Indianapolis (IND)plane plane PAH - IND
    7h 14m
    $97–517

  5. Bus

    1. Take the bus from Flying J - Matthews to Road Ranger Truck Stop - Champaignbus bus Milwaukee
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus Greyhound US0157S
    8h 28m
    $123–263

  6. Bus to Williamson County Regional Airport, fly

    1. Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Indianapolis (IND)plane plane MWA - IND
    8h 30m
    $176–738

  7. Drive, bus to Nashville, fly

    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to Indianapolis (IND)plane plane BNA - IND
    7h 43m
    $107–546

Barkley Regional Airport (PAH) to Indianapolis (IND) flights

Calendar19Weekly Planes
Duration6h 15mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Indianapolis.ExpandLaunch map view
  • Distance: 389.5 mi
  • Duration: 7h 50m

What companies run services between Sikeston, MO, USA and Indianapolis, IN, USA?

You can take a vehicle from Sikeston to Indianapolis Union Station via Flying J - Matthews, Road Ranger Truck Stop - Champaign, and Champaign Intermodal Trans Ctr in around 8h 28m.

Airlines
Train operators
Bus operators
Other operators

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