There are 6 ways to get from Sikeston to Indianapolis by taxi, bus, car, train, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, bus (Greyhound)
best- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus
7h 50m$140–211Drive 327.1 mi
cheapest- Drive from Sikeston to Indianapoliscar 327.1 mi
5h 25m$60–87Drive, train, bus
- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
9h 49m$105–223Drive to Barkley Regional Airport, fly
- Drive from Sikeston to Barkley Regional Airport (PAH)car
- Fly from Barkley Regional Airport (PAH) to Indianapolis (IND)plane PAH - IND
7h 14m$97–517Bus
- Take the bus from Flying J - Matthews to Road Ranger Truck Stop - Champaignbus Milwaukee
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus Greyhound US0157S
8h 28m$116–163Bus to Williamson County Regional Airport, fly
- Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus
- Fly from Williamson County Regional Airport (MWA) to Indianapolis (IND)plane MWA - IND
8h 11m$153–638
Barkley Regional Airport (PAH) to Indianapolis (IND) flights
Questions & Answers
The cheapest way to get from Sikeston to Indianapolis is to drive which costs $55 - $90 and takes 5h 25m.
The fastest way to get from Sikeston to Indianapolis is to drive which takes 5h 25m and costs $55 - $90.
No, there is no direct bus from Sikeston to Indianapolis station. However, there are services departing from Flying J - Matthews and arriving at Indianapolis Union Station via Champaign Intermodal Trans Ctr. The journey, including transfers, takes approximately 8h 28m.
The distance between Sikeston and Indianapolis is 392 miles. The road distance is 329 miles.
The best way to get from Sikeston to Indianapolis without a car is to taxi and bus which takes 7h 50m and costs $140 - $220.
It takes approximately 7h 50m to get from Sikeston to Indianapolis, including transfers.
Sikeston to Indianapolis bus services, operated by Tornado Bus Company, depart from Flying J - Matthews station.
Sikeston to Indianapolis bus services, operated by Tornado Bus Company, arrive at Road Ranger Truck Stop - Champaign station.
Indianapolis is 1h ahead of Sikeston. It is currently 11:23 PM in Sikeston and 12:23 AM in Indianapolis.
Yes, the driving distance between Sikeston to Indianapolis is 329 miles. It takes approximately 5h 25m to drive from Sikeston to Indianapolis.
What companies run services between Sikeston, MO, USA and Indianapolis, IN, USA?
You can take a vehicle from Sikeston to Indianapolis Union Station via Flying J - Matthews, Road Ranger Truck Stop - Champaign, and Champaign Intermodal Trans Ctr in around 8h 28m.
- Website
- united.com
Flights from Barkley Regional Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $85–500
Flights from Barkley Regional Airport to Indianapolis via Houston
- Ave. Duration
- 8h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–800
- Website
- aa.com
Flights from Williamson County Regional Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $95–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fulton Amtrak Station to Champaign-Urbana
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $75–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Flying J - Matthews to Road Ranger Truck Stop - Champaign
- Ave. Duration
- 5h 1m
- Frequency
- Once daily
- Estimated price
- $55–75
- Schedules at
- Tornado Bus Company
- Adult
- $55–75
Bus from Flying J - Matthews to Marathon Gas Station - Marion
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $17–40
- Schedules at
- Tornado Bus Company
- Adult
- $17–40
- Ave. Duration
- 35 min
- Estimated price
- $90–120
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