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How to get fromSikeston to Jacksonvilleby taxi, bus, plane, or car

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There are 5 ways to get from Sikeston to Jacksonville by taxi, bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus to Lambert–St. Louis International Airport, fly to Jacksonville

    best
    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    7h 47m
    $216–696

  2. Drive, bus

    cheapest
    1. Drive from Sikeston to Paducah Bus Stationcar car
    2. Take the bus from Paducah Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    15h 42m
    $122–202

  3. Drive  747.9 mi

    1. Drive from Sikeston to Jacksonvillecar car 747.9 mi
    13h 37m
    $137–198

  4. Taxi to Cape Girardeau Municipal Airport, fly to Orlando Sanford, drive

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Orlando Sanford (SFB)plane plane CGI - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Jacksonvillecar car
    5h 11m
    $296–985

  5. Bus to Memphis, fly to Jacksonville

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Fly from Memphis (MEM) to Jacksonville (JAX)plane plane MEM - JAX
    10h 3m
    $176–667

Lambert–St. Louis International Airport (STL) to Jacksonville (JAX) flights

Calendar57Weekly Planes
Duration3h 36mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sikeston to Jacksonville.ExpandLaunch map view
  • Distance: 931.8 mi
  • Duration: 7h 47m

What companies run services between Sikeston, MO, USA and Jacksonville, FL, USA?

There is no direct connection from Sikeston to Jacksonville. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Jacksonville (JAX), walk to Jia, then take the line 1 bus to JRTC Bay J. Alternatively, you can take a vehicle from Sikeston to Jacksonville via Paducah Bus Station and Atlanta Bus Station in around 15h 42m.

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