There are 3 ways to get from Sikeston to Kentucky by bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus Milwaukee
- Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus Memphis
11h 35m$151–368Drive 276.4 mi
cheapest- Drive from Sikeston to Louisvillecar 276.4 mi
4h 48m$51–73Drive, train, bus
- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
13h 14m$144–293
Questions & Answers
The cheapest way to get from Sikeston to Kentucky is to drive which costs $50 - $75 and takes 4h 48m.
The fastest way to get from Sikeston to Kentucky is to drive which takes 4h 48m and costs $50 - $75.
No, there is no direct bus from Sikeston to Kentucky. However, there are services departing from Flying J - Matthews and arriving at W Jefferson @ S 5th via Tornado Bus Co - West Memphis and Preston @ Vim. The journey, including transfers, takes approximately 11h 35m.
The distance between Sikeston and Kentucky is 541 miles. The road distance is 278 miles.
The best way to get from Sikeston to Kentucky without a car is to bus which takes 11h 35m and costs $150 - $370.
It takes approximately 11h 35m to get from Sikeston to Kentucky, including transfers.
Sikeston to Kentucky bus services, operated by Tornado Bus Company, depart from Flying J - Matthews station.
Sikeston to Kentucky bus services, operated by Tornado Bus Company, arrive at Tornado Bus Co - West Memphis station.
Kentucky is 1h ahead of Sikeston. It is currently 2:12 AM in Sikeston and 3:12 AM in Kentucky.
Yes, the driving distance between Sikeston to Kentucky is 278 miles. It takes approximately 4h 48m to drive from Sikeston to Kentucky.
What companies run services between Sikeston, MO, USA and Kentucky, USA?
You can take a vehicle from Sikeston to W Jefferson @ S 5th via Flying J - Matthews, Tornado Bus Co - West Memphis, La Tropicana - Louisville, KY, and Preston @ Vim in around 11h 35m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fulton Amtrak Station to Champaign-Urbana
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Flying J - Matthews to Tornado Bus Co - West Memphis
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
Bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KY
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a week
- Estimated price
- $75–190
- Schedules at
- tornadobus.com
- Adults 11-59
- $75–190
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Champaign Intermodal Trans Ctr to Indianapolis Union Station
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 601+ hotels available in Kentucky.








