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How to get fromSikeston to Kentuckyby bus, car, or train

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There are 3 ways to get from Sikeston to Kentucky by bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus Milwaukee
    2. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus Memphis
    11h 35m
    $151–368
  2. Drive 276.4 mi

    cheapest
    1. Drive from Sikeston to Louisvillecar car 276.4 mi
    4h 48m
    $51–73
  3. Drive, train, bus

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 14m
    $144–293

Questions & Answers

What companies run services between Sikeston, MO, USA and Kentucky, USA?

You can take a vehicle from Sikeston to W Jefferson @ S 5th via Flying J - Matthews, Tornado Bus Co - West Memphis, La Tropicana - Louisville, KY, and Preston @ Vim in around 11h 35m.

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