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How to get fromSikeston to Kirksvilleby taxi, plane, bus, train, car, or shuttle

Find Transport to Kirksville

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There are 6 ways to get from Sikeston to Kirksville by taxi, plane, bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Cape Girardeau Municipal Airport, fly

    best
    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Kirksville Regional Airport (IRK)plane plane CGI - IRK
    7h 5m
    $289–795

  2. Drive 335 mi

    cheapest
    1. Drive from Sikeston to Kirksvillecar car 335 mi
    5h 53m
    $62–89

  3. Taxi, bus, train

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the train from Kansas City to La Plata Stationtrain train
    12h 26m
    $286–486

  4. Bus, train

    1. Take the bus from Flying J - Matthews to Road Ranger Truck Stop - Champaignbus bus
    2. Take the bus from Champaign Intermodal Trans Ctr to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    12h 39m
    $209–408

  5. Bus to Williamson County Regional Airport, fly

    1. Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Kirksville Regional Airport (IRK)plane plane MWA - IRK
    8h 31m
    $189–651

  6. Taxi, bus, shuttle

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    4. Take a shuttle bus from Bowling Green, Mo to Columbiashuttle bus
    5. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    10h 1m
    $125–167

Cape Girardeau Municipal Airport (CGI) to Kirksville Regional Airport (IRK) flights

Calendar7Weekly Planes
Duration6h 20mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Kirksville.ExpandLaunch map view
  • Distance: 292.4 mi
  • Duration: 7h 5m

What companies run services between Sikeston, MO, USA and Kirksville, MO, USA?

There is no direct connection from Sikeston to Kirksville. However, you can take the taxi to Cape Girardeau Municipal Airport (CGI) airport, fly to Kirksville Regional Airport (IRK), then take the taxi to Kirksville. Alternatively, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to St. Louis, take the train to Kansas City, take the train to La Plata Station, then take the taxi to Kirksville.

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