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How to get fromSikeston to Lexingtonby car, plane, bus, or train

Find Transport to Lexington

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There are 5 ways to get from Sikeston to Lexington by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Barkley Regional Airport, fly

    best
    1. Drive from Sikeston to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Blue Grass Airport (LEX)plane plane PAH - LEX
    7h 50m
    $82–407

  2. Drive  318.1 mi

    cheapest
    1. Drive from Sikeston to Lexingtoncar car 318.1 mi
    5h 30m
    $58–84

  3. Bus, drive

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    14h 43m
    $149–206

  4. Bus to Williamson County Regional Airport, fly

    1. Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Blue Grass Airport (LEX)plane plane MWA - LEX
    11h 49m
    $138–538

  5. Drive, train, bus

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    17h 8m
    $220–362

Barkley Regional Airport (PAH) to Blue Grass Airport (LEX) flights

Calendar19Weekly Planes
Duration6h 15mAverage Duration
Ticket$71Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sikeston to Lexington.ExpandLaunch map view
  • Distance: 307.6 mi
  • Duration: 7h 50m

What companies run services between Sikeston, MO, USA and Lexington, KY, USA?

There is no direct connection from Sikeston to Lexington. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Blue Grass Airport (LEX), walk to Terminal @ Bluegrass Field, take the line 8 bus to Transit Center, then take the line 3 bus to Centre Parkway @ 1349. Alternatively, you can take a vehicle from Sikeston to Lexington via Flying J - Matthews, Tornado Bus Co - West Memphis, La Tropicana - Louisville, KY, Preston @ Vim, S 5th @ W Jefferson, and Middletown Station @ Target in around 14h 43m.

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