There are 5 ways to get from Sikeston to Louisiana by car, train, taxi, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, train (Amtrak)
best- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain City of New Orleans
13h 21m$153–388Drive to Barkley Regional Airport, fly to Lake Charles Regional Airport
cheapest- Drive from Sikeston to Barkley Regional Airport (PAH)car
- Fly from Barkley Regional Airport (PAH) to Lake Charles Regional Airport (LCH)plane PAH - LCH
8h 7m$96–438Taxi, bus (Greyhound)
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to New Orleans Bus Stationbus Greyhound US1173
15h 10m$189–261Drive 533 mi
- Drive from Sikeston to New Orleanscar 533 mi
8h 46m$98–141Taxi, bus to Lambert–St. Louis International Airport, fly to Louis Armstrong New Orleans International Airport
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane STL - MSY
5h 48m$515–993
Barkley Regional Airport (PAH) to Lake Charles Regional Airport (LCH) flights
Comparing Your Travel Options
The cheapest way to get from Sikeston to Louisiana is to drive which costs $95 - $150 and takes 8h 46m.
The fastest way to get from Sikeston to Louisiana is to taxi and bus and fly which takes 5h 48m and costs $500 - $1,000.
The distance between Sikeston and Louisiana is 599 miles. The road distance is 536.2 miles.
The best way to get from Sikeston to Louisiana without a car is to taxi and bus which takes 15h 10m and costs $180 - $270.
It takes approximately 13h 21m to get from Sikeston to Louisiana, including transfers.
Yes, the driving distance between Sikeston to Louisiana is 536 miles. It takes approximately 8h 46m to drive from Sikeston to Louisiana.
There are 1203+ hotels available in Louisiana.
What companies run services between Sikeston, MO, USA and Louisiana, USA?
There is no direct connection from Sikeston to Louisiana. However, you can drive to Fulton Amtrak Station then take the train to New Orleans Union Passenger Terminal. Alternatively, you can take the taxi to Cape Girardeau then take the bus to New Orleans Bus Station.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $95–600
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Dallas
- Ave. Duration
- 4h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 15m
- When
- Sunday
- Estimated price
- $120–650
- Website
- united.com
Flights from Barkley Regional Airport to Lake Charles Regional Airport via Houston
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $75–410
Flights from Barkley Regional Airport to Lake Charles Regional Airport via Chicago O'Hare, Houston
- Ave. Duration
- 10h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fulton Amtrak Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 11h 52m
- Frequency
- Once daily
- Estimated price
- $140–370
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to New Orleans Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
- Ave. Duration
- 35 min
- Estimated price
- $90–120
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide





