There are 5 ways to get from Sikeston to New Orleans by car, plane, train, taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Barkley Regional Airport, fly
best- Drive from Sikeston to Barkley Regional Airport (PAH)car
- Fly from Barkley Regional Airport (PAH) to Louis Armstrong New Orleans International Airport (MSY)plane PAH - MSY
7h 41m$120–617Drive 533 mi
cheapest- Drive from Sikeston to New Orleanscar 533 mi
8h 46m$92–132Drive, train (Amtrak)
- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain City of New Orleans
13h 21m$302–467Taxi, bus (Greyhound)
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to New Orleans Bus Stationbus Greyhound US1173
15h 10m$194–271Taxi, bus to Lambert–St. Louis International Airport, fly
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane STL - MSY
7h 2m$218–752
Barkley Regional Airport (PAH) to Louis Armstrong New Orleans International Airport (MSY) flights
Comparing Your Travel Options
The cheapest way to get from Sikeston to New Orleans is to drive which costs $90 - $140 and takes 8h 46m.
The fastest way to get from Sikeston to New Orleans is to taxi and bus and fly which takes 7h 2m and costs $210 - $750.
The distance between Sikeston and New Orleans is 568 miles. The road distance is 536.2 miles.
The best way to get from Sikeston to New Orleans without a car is to taxi and bus which takes 15h 10m and costs $190 - $280.
It takes approximately 7h 41m to get from Sikeston to New Orleans, including transfers.
Yes, the driving distance between Sikeston to New Orleans is 536 miles. It takes approximately 8h 46m to drive from Sikeston to New Orleans.
There are 1199+ hotels available in New Orleans.
What companies run services between Sikeston, MO, USA and New Orleans, LA, USA?
There is no direct connection from Sikeston to New Orleans. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Louis Armstrong New Orleans International Airport (MSY), walk to Kenner Terminal Parking Garage, then take the bus to Tulane @ Loyola. Alternatively, you can take a vehicle from Sikeston to New Orleans Union Passenger Terminal via Fulton Amtrak Station in around 13h 21m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday to Thursday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Dallas
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Sunday, and Wednesday
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Houston Hobby Apt
- Ave. Duration
- 4h 10m
- When
- Monday to Thursday
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Chicago Midway
- Ave. Duration
- 4h 26m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $140–700
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Austin
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- $140–750
- Website
- united.com
Flights from Barkley Regional Airport to Louis Armstrong New Orleans International Airport via Houston
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $110–600
Flights from Barkley Regional Airport to Louis Armstrong New Orleans International Airport via Chicago O'Hare
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $130–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fulton Amtrak Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 11h 52m
- Frequency
- Once daily
- Estimated price
- $290–450
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to New Orleans Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–35
- Website
- Greyhound
- Ave. Duration
- 35 min
- Estimated price
- $90–120
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide











