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How to get fromSikeston to Panama City Beachby taxi, bus, plane, car, train, or bus (Greyhound)

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There are 9 ways to get from Sikeston to Panama City Beach by taxi, bus, plane, car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus to Lambert–St. Louis International Airport, fly to Northwest Florida Beaches International Airport

    best
    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    6h 21m
    $254–694

  2. Drive 605 mi

    cheapest
    1. Drive from Sikeston to Panama City Beachcar car 605 mi
    11h 23m
    $111–160

  3. Drive, train, bus

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    21h 25m
    $237–475

  4. Bus

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    21h 46m
    $228–521

  5. Taxi, bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    4. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 15m
    $209–635

  6. Taxi to Cape Girardeau Municipal Airport, fly to Pensacola International Airport, bus

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS)plane plane CGI - PNS
    3. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    5h 46m
    $238–611

  7. Taxi, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport, drive

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    4. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 37m
    $212–553

  8. Drive, train, bus via Biloxi

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Biloxi Amtrak Statrain train
    4. Take the bus from Biloxi Transit Center to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    22h 23m
    $249–501

  9. Taxi, bus (Greyhound)

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to Baton Rouge Bus Stationbus bus
    3. Take the bus from Baton Rouge Bus Station to Panama City Beach Bus Stationbus bus
    25h 24m
    $253–433

Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP) flights

Calendar31Weekly Planes
Duration2h 57mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Sikeston to Panama City Beach.ExpandLaunch map view
  • Distance: 814.2 mi
  • Duration: 6h 21m

What companies run services between Sikeston, MO, USA and Panama City Beach, FL, USA?

You can take a vehicle from Sikeston to Panama City Beach via Flying J - Matthews, Tornado Bus Co - West Memphis, Tornado Bus Co - Nashville, Walmart Station Inbound, Korean Vets Blvd & 4Th Ave Wb, Peabody Station Outbound, Fulton Station Outbound, Nashville Bus Station, Tallahassee, and Panama City Beach Bus Station in around 21h 46m.

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