There are 5 ways to get from Sikeston to Pensacola by taxi, bus, plane, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, bus to Lambert–St. Louis International Airport, fly to Pensacola International Airport
best- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane STL - PNS
6h 59m$174–466Drive 556.1 mi
cheapest- Drive from Sikeston to Pensacolacar 556.1 mi
10h 35m$102–147Drive, train, bus
- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Pensacolabus
18h 29m$388–593Taxi, bus, train
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Pensacolabus
20h 18m$279–396Taxi, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane BLV - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi
7h 23m$325–702
Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS) flights
Comparing Your Travel Options
The cheapest way to get from Sikeston to Pensacola is to drive which costs $100 - $150 and takes 10h 35m.
The fastest way to get from Sikeston to Pensacola is to taxi and bus and fly which takes 6h 59m and costs $170 - $470.
The distance between Sikeston and Pensacola is 768 miles. The road distance is 559.3 miles.
The best way to get from Sikeston to Pensacola without a car is to taxi and bus and train which takes 20h 18m and costs $270 - $400.
It takes approximately 6h 59m to get from Sikeston to Pensacola, including transfers.
Yes, the driving distance between Sikeston to Pensacola is 559 miles. It takes approximately 10h 35m to drive from Sikeston to Pensacola.
There are 1566+ hotels available in Pensacola.
What companies run services between Sikeston, MO, USA and Pensacola, FL, USA?
There is no direct connection from Sikeston to Pensacola. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Pensacola International Airport (PNS), walk to 12Th Ave & College Blvd, then take the line 52 bus to ECAT Transfer Station. Alternatively, you can take a vehicle from Sikeston to Pensacola via Fulton Amtrak Station, New Orleans Union Passenger Terminal, Gulfport Amtrak Sta, and Gulfport in around 18h 29m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Pensacola International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $55–320
Flights from Lambert–St. Louis International Airport to Pensacola International Airport via Nashville
- Ave. Duration
- 3h 43m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $60–330
Flights from Lambert–St. Louis International Airport to Pensacola International Airport via Dallas
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- $85–400
- Website
- allegiantair.com
Flights from Midamerica St. Louis Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–380
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $65–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fulton Amtrak Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 11h 52m
- Frequency
- Once daily
- Estimated price
- $290–450
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Cape Girardeau to New Orleans Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Gulfport to Pensacola
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $50–65
- Schedules at
- Omnibus Express
Bus from Gulfport to Pensacola
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $50–65
- Schedules at
- Omnibus Express
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