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How to get fromSikeston to Pensacolaby taxi, bus, plane, car, or train

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There are 6 ways to get from Sikeston to Pensacola by taxi, bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus to Lambert–St. Louis International Airport, fly to Destin–Fort Walton Beach Airport

    best
    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    4. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    7h 13m
    $318–749

  2. Drive  556.1 mi

    cheapest
    1. Drive from Sikeston to Pensacolacar car 556.1 mi
    10h 35m
    $95–138

  3. Drive, train, bus

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Pensacolabus bus
    18h 29m
    $387–592

  4. Taxi, bus

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    4. Take the bus from Biloxi to Pensacolabus bus
    21h 10m
    $268–376

  5. Bus to Memphis, fly to Pensacola International Airport

    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus
    2. Fly from Memphis (MEM) to Pensacola International Airport (PNS)plane plane MEM - PNS
    7h 46m
    $152–526

  6. Taxi, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    4. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    7h 26m
    $326–707

Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar41Weekly Planes
Duration3h 47mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sikeston to Pensacola.ExpandLaunch map view
  • Distance: 818.2 mi
  • Duration: 7h 13m

What companies run services between Sikeston, MO, USA and Pensacola, FL, USA?

There is no direct connection from Sikeston to Pensacola. However, you can take the taxi to Cape Girardeau, take the bus to St Louis Bus Station, walk to CIVIC CENTER station, take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Destin–Fort Walton Beach Airport (VPS), then take the taxi to Pensacola. Alternatively, you can take a vehicle from Sikeston to Pensacola via Fulton Amtrak Station, New Orleans Union Passenger Terminal, Gulfport Amtrak Sta, and Gulfport in around 18h 29m.

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