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How to get fromSikeston to Tupeloby bus (Greyhound), car, taxi, or plane

Find Transport to Tupelo

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There are 3 ways to get from Sikeston to Tupelo by bus (Greyhound), car, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus bus Milwaukee
    2. Take the bus from Memphis Bus Station to Tupelobus bus Greyhound US0610
    5h 43m
    $125–181
  2. Drive  225.5 mi

    cheapest
    1. Drive from Sikeston to Tupelocar car 225.5 mi
    4h 11m
    $42–60
  3. Taxi, fly

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Tupelo Regional Airport (TUP)plane plane CGI - TUP
    5h 21m
    $428–1,418

Cape Girardeau Municipal Airport (CGI) to Tupelo Regional Airport (TUP) flights

Calendar4Weekly Planes
Duration4h 40mAverage Duration
Ticket$332Cheapest Price
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Comparing Your Travel Options

What companies run services between Sikeston, MO, USA and Tupelo, MS, USA?

You can take a vehicle from Sikeston to Tupelo via Flying J - Matthews, Tornado Bus Co - West Memphis, Memphis Bus Station, and Tupelo in around 5h 43m.

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Need to know: Greyhound

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