There are 8 ways to get from Silver Spring to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Washington Union Station to Florence Stationtrain Palmetto / ...
9h 2m$102–242Bus
cheapest- Take the bus from Washington Union Station to Raleigh Bus Stationbus Greyhound US0670 / ...
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus Greyhound US0642S / ...
9h 49m$61–107Drive 405.7 mi
- Drive from Silver Spring to Florencecar 405.7 mi
6h 58m$74–107Fly Ronald Reagan Washington National Airport to Myrtle Beach, bus
- Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane DCA - MYR
- Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus
5h 49m$95–507Bus, train
- Take the bus from Washington Union Station to Fayetteville Bus Stationbus FlixBus N2471 / ...
- Take the train from Fayetteville Amtrak Station to Florence Stationtrain Palmetto / ...
10h 20m$67–127Train to Baltimore-Washington International Airport, fly to Myrtle Beach, bus
- Take the train from Washington Union Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane BWI - MYR
- Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus
6h 19m$325–1,233Subway to Washington Dulles International Airport, fly to Myrtle Beach, bus
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane IAD - MYR
- Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus
8h 51m$75–366Fly Ronald Reagan Washington National Airport to Charlotte Douglas International Airport, bus
- Fly from Ronald Reagan Washington National Airport (DCA) to Charlotte Douglas International Airport (CLT)plane DCA - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
8h 21m$137–794
Silver Spring to Florence by subway and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Silver Spring to Florence is to bus which costs $60 - $110 and takes 9h 49m.
The fastest way to get from Silver Spring to Florence is to fly and bus which takes 5h 49m and costs $95 - $550.
No, there is no direct bus from Silver Spring station to Florence station. However, there are services departing from Washington Union Station and arriving at Florence Bus Station via Raleigh Bus Station. The journey, including transfers, takes approximately 9h 49m.
No, there is no direct train from Silver Spring to Florence station. However, there are services departing from Silver Spring, Red Line Center Platform and arriving at Florence Station via Washington Union Station. The journey, including transfers, takes approximately 9h 2m.
The distance between Silver Spring and Florence is 417 miles. The road distance is 408.1 miles.
The best way to get from Silver Spring to Florence without a car is to train which takes 9h 2m and costs $100 - $250.
It takes approximately 9h 2m to get from Silver Spring to Florence, including transfers.
Silver Spring to Florence bus services, operated by Greyhound USA, depart from Washington Union Station.
Silver Spring to Florence train services, operated by Amtrak, depart from Washington Union Station.
The best way to get from Silver Spring to Florence is to train which takes 9h 2m and costs $100 - $250. Alternatively, you can bus, which costs $60 - $110 and takes 9h 49m.
What companies run services between Silver Spring, MD, USA and Florence, SC, USA?
Amtrak operates a train from Washington Union Station to Florence Station twice daily. Tickets cost $100–240 and the journey takes 7h 48m. Alternatively, you can take a subway from Silver Spring, Red Line Center Platform to Florence Bus Station via Union Station, Red Line Center Platform, Washington Union Station, and Raleigh Bus Station in around 9h 49m.
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Myrtle Beach
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $70–470
Flights from Ronald Reagan Washington National Airport to Myrtle Beach via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $80–500
Flights from Washington Dulles International Airport to Myrtle Beach via Charlotte Douglas International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $50–330
Flights from Ronald Reagan Washington National Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $110–750
Flights from Ronald Reagan Washington National Airport to Charlotte Douglas International Airport via Raleigh/Durham
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $110–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Washington Union Station to Florence Station
- Ave. Duration
- 7h 48m
- Frequency
- Twice daily
- Estimated price
- $100–240
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Florence Station
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- $20–50
- Website
- Amtrak
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–18
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Florence Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $10–17
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Florence Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $10–17
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Florence Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $10–17
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–20
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $7–12
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Silver Spring to Florence bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Silver Spring to Florence train services, operated by Amtrak, arrive at Florence Station.
Yes, the driving distance between Silver Spring to Florence is 408 miles. It takes approximately 6h 58m to drive from Silver Spring to Florence.
Book your Silver Spring to Florence bus tickets online with Omio.
There are 46+ hotels available in Florence.





