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How to get fromSimpsonville to Harrisburg, Paby plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

Find Transport to Harrisburg, Pa

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There are 6 ways to get from Simpsonville to Harrisburg, Pa by plane, bus (Greyhound, Flixbus), taxi, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Harrisburg International Airport (MDT)plane plane GSP - MDT
    4h 53m
    $115–468

  2. Drive 543.6 mi

    cheapest
    1. Drive from Simpsonville to Harrisburg, Pacar car 543.6 mi
    10h 19m
    $100–144

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    16h 32m
    $159–348

  4. Taxi, bus, train

    1. Take the taxi from Simpsonville to Servicios Zapata - Spartanburgtaxi taxi
    2. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    3. Take the train from Charlotte Amtrak Station to 30th Street Stationtrain train
    4. Take the train from 30th Street Station to Harrisburgtrain train
    18h 5m
    $313–638

  5. Fly to Philadelphia International Airport, train

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Philadelphia International Airport (PHL)plane plane GSP - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    5h 44m
    $182–769

  6. Bus via Winston-Salem

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    20h 7m
    $166–384

Greenville–Spartanburg International Airport (GSP) to Harrisburg International Airport (MDT) flights

Calendar100Weekly Planes
Duration4h 53mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Simpsonville to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 496.5 mi
  • Duration: 4h 53m

What companies run services between Simpsonville, SC, USA and Harrisburg, Pa, PA, USA?

United Airlines, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Harrisburg International Airport (MDT) hourly. Alternatively, you can take a vehicle from Simpsonville to Harrisburg Bus Station via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, and Baltimore Downtown Bus Station in around 16h 32m.

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