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How to get fromSimpsonville to Louisvilleby plane, bus (Greyhound, Flixbus), or car

Find Transport to Louisville

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There are 3 ways to get from Simpsonville to Louisville by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Louisville International Airport (SDF)plane plane GSP - SDF
    4h 46m
    $140–699
  2. Drive  389.6 mi

    cheapest
    1. Drive from Simpsonville to Louisvillecar car 389.6 mi
    8h 18m
    $72–103
  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
    14h 37m
    $134–212

Greenville–Spartanburg International Airport (GSP) to Louisville International Airport (SDF) flights

Calendar106Weekly Planes
Duration4h 26mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

What companies run services between Simpsonville, SC, USA and Louisville, KY, USA?

Delta, Southwest Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Louisville International Airport (SDF) hourly. Alternatively, you can take a vehicle from Simpsonville to Louisville Bus Station via Taqueria Guadalajara - Greenville, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 14h 37m.

Airlines
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