There are 8 ways to get from Sioux City to Gainesville by bus, plane, bus (Greyhound, Flixbus), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Sioux Falls, fly to Gainesville Regional Airport
best- Take the bus from Sioux City to Sioux Fallsbus
- Fly from Sioux Falls (FSD) to Gainesville Regional Airport (GNV)plane FSD - GNV
10h 30m$147–613Bus
- Take the bus from Sioux City to Kansas Citybus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Gainesvillebus
30h$236–384Bus, train
- Take the bus from Sioux City to Omahabus
- Take the bus from Omaha, NE to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Jacksonvilletrain
- Take the bus from Jacksonville to Gainesvillebus
2d 3h$494–1,084Drive 1,356.3 mi
- Drive from Sioux City to Gainesvillecar 1,356.3 mi
24h 17m$248–358Fly Sioux Gateway Airport/Col. Bud Day Field to Jacksonville, bus
- Fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Jacksonville (JAX)plane SUX - JAX
- Take the bus from Jacksonville to Gainesvillebus
13h 33m$152–644Bus to Omaha, fly to Gainesville Regional Airport
- Take the bus from Sioux City to Omahabus
- Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane OMA - GNV
9h 46m$147–649Bus to Omaha, fly to Orlando, bus
- Take the bus from Sioux City to Omahabus
- Fly from Omaha (OMA) to Orlando (MCO)plane OMA - MCO
- Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus
10h 37m$256–689Bus to Sioux Falls, fly to Orlando Sanford, drive
- Take the bus from Sioux City to Sioux Fallsbus
- Fly from Sioux Falls (FSD) to Orlando Sanford (SFB)plane FSD - SFB
- Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar
8h 42m$175–641
Sioux City to Gainesville by bus
Comparing Your Travel Options
The cheapest way to get from Sioux City to Gainesville is to bus which costs $230 - $390 and takes 30h.
The fastest way to get from Sioux City to Gainesville is to bus and fly and drive which takes 8h 42m and costs $170 - $650.
No, there is no direct bus from Sioux City to Gainesville. However, there are services departing from Sioux City and arriving at Gainesville via Kansas City Bus Station, St Louis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 30h.
The distance between Sioux City and Gainesville is 1365 miles. The road distance is 1364.3 miles.
The best way to get from Sioux City to Gainesville without a car is to bus which takes 30h and costs $230 - $390.
It takes approximately 10h 30m to get from Sioux City to Gainesville, including transfers.
Sioux City to Gainesville bus services, operated by Jefferson Lines, depart from Sioux City station.
Sioux City to Gainesville bus services, operated by Jefferson Lines, arrive at Kansas City station.
Gainesville is 1h ahead of Sioux City. It is currently 1:08 AM in Sioux City and 2:08 AM in Gainesville.
Yes, the driving distance between Sioux City to Gainesville is 1364 miles. It takes approximately 24h 17m to drive from Sioux City to Gainesville.
What companies run services between Sioux City, IA, USA and Gainesville, FL, USA?
You can take a bus from Sioux City to Gainesville via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 30h.
- Website
- delta.com
Flights from Sioux Falls to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Gainesville Regional Airport via Minneapolis, Atlanta
- Ave. Duration
- 7h 53m
- When
- Every day
- Estimated price
- $110–550
Flights from Omaha to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $110–600
Flights from Omaha to Orlando via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Jacksonville
- Ave. Duration
- 34h 52m
- Frequency
- Once daily
- Estimated price
- $380–900
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux City to Sioux Falls
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–50
- Book at
- Jefferson Lines
- Adult
- $30–50
Bus from Sioux City to Kansas City
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $75–110
- Book at
- Jefferson Lines
- Adult
- $75–110
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux City to Sioux Falls
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–50
- Book at
- Jefferson Lines
- Adult
- $30–50
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Booking & Getting There
There are 276+ hotels available in Gainesville.






