There are 4 ways to get from Sioux City to Indianapolis by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Sioux Gateway Airport/Col. Bud Day Field
best- Fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Indianapolis (IND)plane SUX - IND
6h 56m$118–577Bus
- Take the bus from Sioux City to Omahabus
- Take the bus from Omaha, NE to Des Moinesbus
- Take the bus from Des Moines to Indianapolis Union Stationbus
15h 30m$124–215Drive 645.1 mi
- Drive from Sioux City to Indianapoliscar 645.1 mi
11h 4m$118–171Bus to Sioux Falls, fly
- Take the bus from Sioux City to Sioux Fallsbus
- Fly from Sioux Falls (FSD) to Indianapolis (IND)plane FSD - IND
8h 2m$147–613
Sioux City to Indianapolis by bus
Questions & Answers
The cheapest way to get from Sioux City to Indianapolis is to drive which costs $110 - $170 and takes 11h 4m.
The fastest way to get from Sioux City to Indianapolis is to fly which takes 6h 56m and costs $110 - $600.
No, there is no direct bus from Sioux City to Indianapolis station. However, there are services departing from Sioux City and arriving at Indianapolis Union Station via Omaha, NE and Des Moines. The journey, including transfers, takes approximately 15h 30m.
The distance between Sioux City and Indianapolis is 583 miles. The road distance is 648.9 miles.
The best way to get from Sioux City to Indianapolis without a car is to bus which takes 15h 30m and costs $120 - $220.
It takes approximately 6h 56m to get from Sioux City to Indianapolis, including transfers.
Sioux City to Indianapolis bus services, operated by Jefferson Lines, depart from Sioux City station.
The best way to get from Sioux City to Indianapolis is to fly which takes 6h 56m and costs $110 - $600. Alternatively, you can bus, which costs $120 - $220 and takes 15h 30m.
Sioux City to Indianapolis bus services, operated by Jefferson Lines, arrive at Omaha station.
Indianapolis is 1h ahead of Sioux City. It is currently 6:34 AM in Sioux City and 7:34 AM in Indianapolis.
What companies run services between Sioux City, IA, USA and Indianapolis, IN, USA?
United Airlines flies from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Indianapolis (IND) 3 times a day. Alternatively, you can take a bus from Sioux City to Indianapolis Union Station via Omaha, NE and Des Moines in around 15h 30m.
- Website
- united.com
Flights from Sioux Gateway Airport/Col. Bud Day Field to Indianapolis via Chicago O'Hare
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $95–550
Flights from Sioux Falls to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Indianapolis via Denver
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $170–800
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Sioux City to Sioux Falls
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $30–50
- Book at
- Jefferson Lines
- Adult
- $30–50
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More Questions & Answers
Yes, the driving distance between Sioux City to Indianapolis is 649 miles. It takes approximately 11h 4m to drive from Sioux City to Indianapolis.
There are 876+ hotels available in Indianapolis.



