There are 8 ways to get from Sioux City to Louisville by plane, bus (Greyhound, Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Sioux Gateway Airport/Col. Bud Day Field to Louisville International Airport
best- Fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Louisville International Airport (SDF)plane SUX - SDF
5h 49m$122–578Bus
- Take the bus from Sioux City to Omahabus
- Take the bus from Omaha to Indianapolisbus
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
17h 10mDrive 759.4 mi
- Drive from Sioux City to Louisvillecar 759.4 mi
12h 55m$139–201Fly Sioux Gateway Airport/Col. Bud Day Field to Blue Grass Airport, drive
- Fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Blue Grass Airport (LEX)plane SUX - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
6h 1m$194–894Bus to Sioux Falls, fly to Louisville International Airport
- Take the bus from Sioux City to Sioux Fallsbus
- Fly from Sioux Falls (FSD) to Louisville International Airport (SDF)plane FSD - SDF
8h 20m$156–614Fly Sioux Gateway Airport/Col. Bud Day Field to Covington, bus
- Fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Covington (CVG)plane SUX - CVG
- Take the bus from Cincinnati to Louisvillebus
8h 23m$142–672Bus to Omaha, fly to Louisville International Airport
- Take the bus from Sioux City to Omahabus
- Fly from Omaha (OMA) to Louisville International Airport (SDF)plane OMA - SDF
8h 55m$156–700Bus via Des Moines
- Take the bus from Sioux City to Omahabus
- Take the bus from Omaha, NE to Des Moinesbus
- Take the bus from Des Moines to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville Bus Stationbus
18h 20m$146–275
Sioux Gateway Airport/Col. Bud Day Field (SUX) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Sioux City to Louisville is to drive which costs $130 - $200 and takes 12h 55m.
The fastest way to get from Sioux City to Louisville is to fly which takes 5h 49m and costs $120 - $600.
No, there is no direct bus from Sioux City to Louisville station. However, there are services departing from Sioux City and arriving at Louisville Bus Station via Omaha and Indianapolis Union Station. The journey, including transfers, takes approximately 17h 10m.
The distance between Sioux City and Louisville is 649 miles. The road distance is 763.8 miles.
The best way to get from Sioux City to Louisville without a car is to bus which takes 17h 10m and costs .
It takes approximately 5h 49m to get from Sioux City to Louisville, including transfers.
Sioux City to Louisville bus services, operated by Jefferson Lines, depart from Sioux City station.
The best way to get from Sioux City to Louisville is to fly which takes 5h 49m and costs $120 - $600. Alternatively, you can bus, which costs and takes 17h 10m.
Sioux City to Louisville bus services, operated by Jefferson Lines, arrive at Omaha station.
Louisville is 1h ahead of Sioux City. It is currently 8:37 PM in Sioux City and 9:37 PM in Louisville.
What companies run services between Sioux City, IA, USA and Louisville, KY, USA?
United Airlines and Southwest Airlines fly from Sioux Gateway Airport/Col. Bud Day Field (SUX) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from Sioux City to Louisville Bus Station via Omaha and Indianapolis Union Station in around 17h 10m.
- Website
- united.com
Flights from Sioux Gateway Airport/Col. Bud Day Field to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 6h 43m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Gateway Airport/Col. Bud Day Field to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $160–850
Flights from Sioux Falls to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $110–550
Flights from Sioux Falls to Louisville International Airport via Denver
- Ave. Duration
- 7h 43m
- When
- Every day
- Estimated price
- $180–800
Flights from Sioux Gateway Airport/Col. Bud Day Field to Covington via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $110–600
Flights from Omaha to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $130–650
- Website
- delta.com
Flights from Sioux Falls to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $110–600
Flights from Sioux Falls to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $160–700
Flights from Omaha to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $150–750
Flights from Omaha to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $180–850
Flights from Omaha to Louisville International Airport via Detroit
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $160–750
- Website
- southwest.com
Flights from Sioux Gateway Airport/Col. Bud Day Field to Louisville International Airport via Denver
- Ave. Duration
- 6h 15m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $180–800
Flights from Sioux Gateway Airport/Col. Bud Day Field to Covington via Denver
- Ave. Duration
- 6h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $200–850
Flights from Omaha to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $120–650
Flights from Omaha to Louisville International Airport via Nashville
- Ave. Duration
- 4h 42m
- When
- Saturday and Sunday
- Estimated price
- $130–700
Flights from Omaha to Louisville International Airport via Dallas
- Ave. Duration
- 6h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–900
- Website
- aa.com
Flights from Sioux Falls to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Sioux Falls to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 40m
- When
- Every day
- Estimated price
- $180–800
Flights from Omaha to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $190–850
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Sioux City to Sioux Falls
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–50
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
Bus from Sioux City to Omaha
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $30–45
- Website
- example.com
Bus from Omaha to Indianapolis
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Schedules at
- example.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $21–45
- Website
- https://www.greyhound.com/
Bus from Des Moines to Indianapolis Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a day
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Schedules at
- greyhound.com
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Schedules at
- greyhound.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Website
- example.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cincinnati to Louisville
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
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More Questions & Answers
Yes, the driving distance between Sioux City to Louisville is 764 miles. It takes approximately 12h 55m to drive from Sioux City to Louisville.
There are 605+ hotels available in Louisville.










