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How to get fromSioux Falls to Cape Girardeauby plane, taxi, bus (Greyhound), car, bus, or train

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There are 8 ways to get from Sioux Falls to Cape Girardeau by plane, taxi, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barkley Regional Airport, taxi

    best
    1. Fly from Sioux Falls (FSD) to Barkley Regional Airport (PAH)plane plane FSD - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    8h 13m
    $222–582

  2. Fly to Cape Girardeau Municipal Airport

    cheapest
    1. Fly from Sioux Falls (FSD) to Cape Girardeau Municipal Airport (CGI)plane plane FSD - CGI
    6h 41m
    $104–440

  3. Bus

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    17h 34m
    $156–260

  4. Drive 706 mi

    1. Drive from Sioux Falls to Cape Girardeaucar car 706 mi
    11h 40m
    $129–187

  5. Fly to Lambert–St. Louis International Airport, bus

    1. Fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL)plane plane FSD - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    9h 6m
    $128–598

  6. Fly to Williamson County Regional Airport, taxi

    1. Fly from Sioux Falls (FSD) to Williamson County Regional Airport (MWA)plane plane FSD - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    7h 25m
    $206–552

  7. Fly to Nashville, bus, taxi

    1. Fly from Sioux Falls (FSD) to Nashville (BNA)plane plane FSD - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    9h 56m
    $218–628

  8. Bus, train

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    19h 54m
    $210–376

Sioux Falls (FSD) to Barkley Regional Airport (PAH) flights

Calendar14Weekly Planes
Duration6h 4mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Cape Girardeau.ExpandLaunch map view
  • Distance: 680.4 mi
  • Duration: 8h 13m

What companies run services between Sioux Falls, SD, USA and Cape Girardeau, MO, USA?

You can take a bus from The Bus Stop to Cape Girardeau via Maple/Career NE corner, Sioux Falls, Kansas City, Kansas City Bus Station, St Louis Bus Station, and Cape Girardeau in around 17h 34m. Alternatively, United Airlines, Corporate Flight Management Inc, and American Airlines fly from Sioux Falls (FSD) to Cape Girardeau Municipal Airport (CGI) 4 times a day.

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