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How to get fromSioux Falls to Chicagoby plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

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There are 7 ways to get from Sioux Falls to Chicago by plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD)plane plane FSD - ORD
    4h
    $48–276

  2. Bus, train via Minneapolis

    1. Take the bus from Sioux Falls to Minneapolisbus bus Jefferson Lines 702 / ...
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    15h 17m
    $288–486

  3. Bus

    1. Take the bus from Sioux Falls to Omahabus bus Jefferson Lines 706
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus Greyhound US0123S
    15h 35m
    $132–206

  4. Drive  537.4 mi

    1. Drive from Sioux Falls to Chicagocar car 537.4 mi
    10h 31m
    $99–142

  5. Fly to Chicago Midway International Airport

    1. Fly from Sioux Falls (FSD) to Chicago Midway International Airport (MDW)plane plane FSD - MDW
    5h 50m
    $64–366

  6. Bus, train

    1. Take the bus from Sioux Falls to Minneapolis-St. Paulbus bus Jefferson Lines 926
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    17h 53m
    $298–464

  7. Bus via Minneapolis

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the bus from Minneapolis Bus Station to Milwaukee Mitchell Airportbus bus
    3. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    17h 57m
    $158–226

Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD) flights

Calendar108Weekly Planes
Duration2h 29mAverage Duration
Ticket$45Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sioux Falls to Chicago.ExpandLaunch map view
  • Distance: 482.1 mi
  • Duration: 4h

What companies run services between Sioux Falls, SD, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from The Bus Stop to Chicago Bus Station via Maple/Career NE corner, Sioux Falls, and Omaha, NE in around 15h 35m.

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Want to know more about travelling around United States

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