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How to get fromSioux Falls to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 8 ways to get from Sioux Falls to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Sioux Falls (FSD) to Mcghee Tyson Airport (TYS)plane plane FSD - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 43m
    $172–818

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Sioux Falls (FSD) to Asheville Regional Airport (AVL)plane plane FSD - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 56m
    $110–474

  3. Bus, drive

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Columbus - Mound Stbus bus
    4. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    40h 18m
    $246–482

  4. Bus, train, drive

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the train from Kansas City to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carytrain train
    4. Take the train from Cary to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    2d 4h
    $636–1,312

  5. Drive 1,133.2 mi

    1. Drive from Sioux Falls to Great Smoky Mountainscar car 1,133.2 mi
    20h 11m
    $207–299

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Sioux Falls (FSD) to Greenville–Spartanburg International Airport (GSP)plane plane FSD - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    9h 22m
    $166–736

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Sioux Falls (FSD) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane FSD - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 8m
    $156–656

  8. Bus, drive via New York

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    5. Drive from Knoxville, TN to Great Smoky Mountainscar car
    2d 4h
    $388–614

Sioux Falls (FSD) to Mcghee Tyson Airport (TYS) flights

Calendar76Weekly Planes
Duration5h 56mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 925.4 mi
  • Duration: 7h 43m

What companies run services between Sioux Falls, SD, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Sioux Falls to Great Smoky Mountains. However, you can take the line 8 bus to 4th Ave/Presentation NE corner, walk to Sioux Falls (FSD) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from The Bus Stop to Great Smoky Mountains via Maple/Career NE corner, Sioux Falls, Omaha, NE, Chicago, Columbus, Winston Salem(Trans Center), and Asheville, NC in around 40h 18m.

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