There are 5 ways to get from Sioux Falls to Iowa City by bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Sioux Falls to Omahabus Jefferson Lines 706
- Take the bus from Omaha, NE to Iowa Citybus Greyhound US0123S
10h 35m$92–142Drive 377.5 mi
cheapest- Drive from Sioux Falls to Iowa Citycar 377.5 mi
6h 23m$69–100Fly to The Eastern Iowa Airport, bus
- Fly from Sioux Falls (FSD) to The Eastern Iowa Airport (CID)plane FSD - CID
- Take the bus from GTC Bay 9 to Court St Transportation Centerbus
7h 59mFly to Quad City International Airport, bus
- Fly from Sioux Falls (FSD) to Quad City International Airport (MLI)plane FSD - MLI
- Take the bus from Moline Center Station to Iowa Citybus
8h 50m$78–398Fly to Chicago O'Hare International Airport, bus
- Fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD)plane FSD - ORD
- Take the bus from Chicago Bus Station to Iowa Citybus
9h 34m$86–340
Sioux Falls (FSD) to The Eastern Iowa Airport (CID) flights
Comparing Your Travel Options
The cheapest way to get from Sioux Falls to Iowa City is to drive which costs $65 - $100 and takes 6h 23m.
The fastest way to get from Sioux Falls to Iowa City is to drive which takes 6h 23m and costs $65 - $100.
No, there is no direct bus from Sioux Falls to Iowa City. However, there are services departing from The Bus Stop and arriving at Iowa City via Sioux Falls and Omaha, NE. The journey, including transfers, takes approximately 10h 35m.
The distance between Sioux Falls and Iowa City is 447 miles. The road distance is 379.7 miles.
The best way to get from Sioux Falls to Iowa City without a car is to bus which takes 10h 35m and costs $90 - $150.
It takes approximately 10h 35m to get from Sioux Falls to Iowa City, including transfers.
Sioux Falls to Iowa City bus services, operated by Jefferson Lines, depart from Sioux Falls station.
Sioux Falls to Iowa City bus services, operated by Jefferson Lines, arrive at Omaha station.
Yes, the driving distance between Sioux Falls to Iowa City is 380 miles. It takes approximately 6h 23m to drive from Sioux Falls to Iowa City.
There are 52+ hotels available in Iowa City.
What companies run services between Sioux Falls, SD, USA and Iowa City, IA, USA?
You can take a bus from The Bus Stop to Iowa City via Maple/Career NE corner, Sioux Falls, and Omaha, NE in around 10h 35m.
- Website
- united.com
Flights from Sioux Falls to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $70–390
Flights from Sioux Falls to The Eastern Iowa Airport via Denver
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $100–480
Flights from Sioux Falls to Quad City International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $65–380
Flights from Sioux Falls to Quad City International Airport via Denver
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $100–490
Flights from Sioux Falls to Chicago O'Hare International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $45–270
- Website
- aa.com
Flights from Sioux Falls to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $70–390
Flights from Sioux Falls to The Eastern Iowa Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $110–550
Flights from Sioux Falls to Quad City International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $65–380
Flights from Sioux Falls to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 23m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $110–550
Flights from Sioux Falls to Chicago O'Hare International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $45–270
- Website
- delta.com
Flights from Sioux Falls to The Eastern Iowa Airport via Minneapolis
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $55–340
Flights from Sioux Falls to Chicago O'Hare International Airport via Minneapolis
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $45–280
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Omaha
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Omaha, NE to Iowa City
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Moline Center Station to Iowa City
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $10–16
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1-319-362-0375
- Website
- 380 Express Corridor Rides
Bus from GTC Bay 9 to Court St Transportation Center
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
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