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How to get fromSioux Falls to Jacksonvilleby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 8 ways to get from Sioux Falls to Jacksonville by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Sioux Falls (FSD) to Jacksonville (JAX)plane plane FSD - JAX
    7h 52m
    $122–554

  2. Bus via Kansas City

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    33h 30m
    $276–506

  3. Bus, train

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    2d 4h
    $632–1,334

  4. Drive 1,448.4 mi

    1. Drive from Sioux Falls to Jacksonvillecar car 1,448.4 mi
    25h 50m
    $265–382

  5. Fly to Brunswick Golden Isles Airport, bus

    1. Fly from Sioux Falls (FSD) to Brunswick Golden Isles Airport (BQK)plane plane FSD - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    9h 18m
    $138–530

  6. Fly to Gainesville Regional Airport, bus

    1. Fly from Sioux Falls (FSD) to Gainesville Regional Airport (GNV)plane plane FSD - GNV
    2. Take the bus from Gainesville to Jacksonvillebus bus
    11h 5m
    $124–522

  7. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha to Champaignbus bus
    3. Take the bus from Champaign Intermodal Trans Ctr to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to La Grange Bus Stationbus bus
    5. Take the bus from La Grange Bus Station to Jacksonvillebus bus
    41h 40m

  8. Bus, train via Kansas City

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the train from Kansas City to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    2d 6h
    $746–1,546

Sioux Falls (FSD) to Jacksonville (JAX) flights

Calendar62Weekly Planes
Duration6h 44mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Jacksonville.ExpandLaunch map view
  • Distance: 1,244.8 mi
  • Duration: 7h 52m

What companies run services between Sioux Falls, SD, USA and Jacksonville, FL, USA?

Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to Jacksonville (JAX) every 3 hours. Alternatively, you can take a bus from The Bus Stop to Jacksonville via Maple/Career NE corner, Sioux Falls, Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 33h 30m.

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