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How to get fromSioux Falls to Mesaby plane, bus, train, bus (Greyhound), or car

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There are 5 ways to get from Sioux Falls to Mesa by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Phoenix

    best
    1. Fly from Sioux Falls (FSD) to Phoenix (PHX)plane plane FSD - PHX
    5h 16m
    $124–414

  2. Fly to Phoenix-Mesa Gateway Airport

    cheapest
    1. Fly from Sioux Falls (FSD) to Phoenix-Mesa Gateway Airport (AZA)plane plane FSD - AZA
    6h 6m
    $108–468

  3. Bus, train

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the train from Kansas City to Flagstafftrain train
    3. Take the bus from Flagstaff Train Station to Tempebus bus
    38h 42m
    $530–1,050

  4. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    4. Take the bus from Las Vegas Strip to Tempebus bus
    42h 38m
    $350–614

  5. Drive 1,366.2 mi

    1. Drive from Sioux Falls to Mesacar car 1,366.2 mi
    25h 7m
    $250–361

Sioux Falls (FSD) to Phoenix (PHX) flights

Calendar101Weekly Planes
Duration5h 29mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Mesa.ExpandLaunch map view
  • Distance: 1,095.9 mi
  • Duration: 5h 16m

What companies run services between Sioux Falls, SD, USA and Mesa, AZ, USA?

American Airlines, United Airlines, and two other airlines fly from Sioux Falls (FSD) to Phoenix (PHX) hourly. Alternatively, you can take a bus from The Bus Stop to University Dr & Mesa Dr via Maple/Career NE corner, Sioux Falls, Omaha, NE, Denver Union Station, Las Vegas Bus Terminal, Las Vegas Strip, Tempe, and University Dr & Rural Rd in around 42h 38m.

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