There are 7 ways to get from Sioux Falls to Milwaukee by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to General Mitchell International Airport
best- Fly from Sioux Falls (FSD) to General Mitchell International Airport (MKE)plane FSD - MKE
5h 13m$90–504Fly to Chicago O'Hare International Airport, bus
cheapest- Fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD)plane FSD - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
5h 38m$60–296Bus
- Take the bus from Sioux Falls to Minneapolisbus Jefferson Lines 702 / ...
- Take the bus from Minneapolis Bus Station to Milwaukee Intermodal Stationbus Greyhound US0150 / ...
13h 10m$146–216Drive 499.1 mi
- Drive from Sioux Falls to Milwaukeecar 499.1 mi
8h 5m$92–132Bus, drive, train
- Take the bus from Sioux Falls to Fairmontbus
- Drive from Fairmont to Mankatocar
- Take the bus from Mankato to Minneapolis-St. Paulbus
- Take the train from St. Paul-Minneapolis to Milwaukeetrain
15h 2m$134–304Bus via Milwaukee Mitchell Airport
- Take the bus from Sioux Falls to Minneapolisbus Jefferson Lines 702 / ...
- Take the bus from Minneapolis Bus Station to Milwaukee Mitchell Airportbus FlixBus 2548
15h 35m$120–184Bus, train
- Take the bus from Sioux Falls to Minneapolis-St. Paulbus Jefferson Lines 926
- Take the train from St. Paul-Minneapolis to Milwaukeetrain Borealis / ...
16h 9m$154–304
Sioux Falls (FSD) to General Mitchell International Airport (MKE) flights
Comparing Your Travel Options
The cheapest way to get from Sioux Falls to Milwaukee is to drive which costs $90 - $140 and takes 8h 5m.
The fastest way to get from Sioux Falls to Milwaukee is to fly which takes 5h 13m and costs $85 - $550.
No, there is no direct bus from Sioux Falls to Milwaukee station. However, there are services departing from The Bus Stop and arriving at Milwaukee Intermodal Station via Sioux Falls and Minneapolis Bus Station. The journey, including transfers, takes approximately 13h 10m.
The distance between Sioux Falls and Milwaukee is 459 miles. The road distance is 502 miles.
The best way to get from Sioux Falls to Milwaukee without a car is to bus which takes 13h 10m and costs $140 - $220.
It takes approximately 5h 13m to get from Sioux Falls to Milwaukee, including transfers.
Sioux Falls to Milwaukee bus services, operated by Jefferson Lines, depart from Sioux Falls station.
The best way to get from Sioux Falls to Milwaukee is to fly which takes 5h 13m and costs $85 - $550. Alternatively, you can bus, which costs $140 - $220 and takes 13h 10m.
Sioux Falls to Milwaukee bus services, operated by Jefferson Lines, arrive at Minneapolis station.
Yes, the driving distance between Sioux Falls to Milwaukee is 502 miles. It takes approximately 8h 5m to drive from Sioux Falls to Milwaukee.
What companies run services between Sioux Falls, SD, USA and Milwaukee, WI, USA?
Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from The Bus Stop to Milwaukee Intermodal Station via Maple/Career NE corner, Sioux Falls, and Minneapolis Bus Station in around 13h 10m.
- Website
- united.com
Flights from Sioux Falls to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $85–550
Flights from Sioux Falls to General Mitchell International Airport via Denver
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $160–750
Flights from Sioux Falls to Chicago O'Hare International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $45–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 48m
- Frequency
- 3 times a day
- Estimated price
- $75–190
- Website
- Amtrak
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 48m
- Frequency
- 3 times a day
- Estimated price
- $75–190
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Minneapolis
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Estimated price
- $65–95
- Book at
- Jefferson Lines
- Adult
- $65–95
Bus from Minneapolis Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $80–120
- Book at
- Jefferson Lines
- Adult
- $80–120
Bus from Sioux Falls to Fairmont
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
Bus from Sioux Falls to Minneapolis
- Ave. Duration
- 4h 50m
- Frequency
- Twice daily
- Estimated price
- $65–95
- Book at
- Jefferson Lines
- Adult
- $65–95
Bus from Sioux Falls to Minneapolis-St. Paul
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $75–110
- Book at
- Jefferson Lines
- Adult
- $75–110
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Booking & Getting There
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