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How to get fromSioux Falls to Milwaukeeby plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

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There are 6 ways to get from Sioux Falls to Milwaukee by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Sioux Falls (FSD) to General Mitchell International Airport (MKE)plane plane FSD - MKE
    5h 19m
    $90–474

  2. Fly to Chicago O'Hare International Airport, bus

    cheapest
    1. Fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD)plane plane FSD - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 44m
    $60–300

  3. Bus

    1. Take the bus from Sioux Falls to Minneapolisbus bus Jefferson 702 / ...
    2. Take the bus from Minneapolis Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150 / ...
    13h 5m
    $116–212

  4. Drive 499.1 mi

    1. Drive from Sioux Falls to Milwaukeecar car 499.1 mi
    8h 5m
    $92–132

  5. Bus, train

    1. Take the bus from Sioux Falls to Minneapolisbus bus Jefferson 702 / ...
    2. Take the train from St. Paul-Minneapolis to Milwaukeetrain train Borealis / ...
    14h 4m
    $168–324

  6. Bus via Milwaukee Mitchell Airport

    1. Take the bus from Sioux Falls to Minneapolisbus bus Jefferson 702 / ...
    2. Take the bus from Minneapolis Bus Station to Milwaukee Mitchell Airportbus bus FlixBus 2548
    15h 30m
    $124–200

Sioux Falls (FSD) to General Mitchell International Airport (MKE) flights

Calendar102Weekly Planes
Duration5h 15mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Milwaukee.ExpandLaunch map view
  • Distance: 456.4 mi
  • Duration: 5h 19m

What companies run services between Sioux Falls, SD, USA and Milwaukee, WI, USA?

Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from The Bus Stop to Milwaukee Intermodal Station via Maple/Career NE corner, Sioux Falls, and Minneapolis Bus Station in around 13h 5m.

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