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How to get fromSioux Falls to Mississippiby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Sioux Falls to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Sioux Falls (FSD) to Memphis (MEM)plane plane FSD - MEM
    5h 56m
    $194–928

  2. Fly to Gulfport-Biloxi Regional Airport

    cheapest
    1. Fly from Sioux Falls (FSD) to Gulfport-Biloxi Regional Airport (GPT)plane plane FSD - GPT
    6h 18m
    $112–516

  3. Bus

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jacksonbus bus
    27h 10m
    $226–352

  4. Bus, train via Saint Paul

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksontrain train
    31h 52m
    $698–1,136

  5. Drive  990.1 mi

    1. Drive from Sioux Falls to Jacksoncar car 990.1 mi
    17h 30m
    $181–261

  6. Fly to Jackson/Vicksburg

    1. Fly from Sioux Falls (FSD) to Jackson/Vicksburg (JAN)plane plane FSD - JAN
    6h 35m
    $142–532

  7. Bus, train

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Jacksontrain train
    32h 19m
    $542–856

  8. Bus, train #2

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Jacksontrain train
    32h 24m
    $542–866

Sioux Falls (FSD) to Memphis (MEM) flights

Calendar93Weekly Planes
Duration5h 51mAverage Duration
Ticket$174Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sioux Falls to Mississippi.ExpandLaunch map view
  • Distance: 701.3 mi
  • Duration: 5h 56m

What companies run services between Sioux Falls, SD, USA and Mississippi, USA?

Delta, American Airlines, and United Airlines fly from Sioux Falls (FSD) to Memphis (MEM) hourly. Alternatively, you can take a bus from The Bus Stop to Jackson via Maple/Career NE corner, Sioux Falls, Kansas City, Kansas City Bus Station, and St Louis Bus Station in around 27h 10m.

Airlines
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