There are 6 ways to get from Sioux Falls to Missouri by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Lambert–St. Louis International Airport
best- Fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL)plane FSD - STL
5h 35m$100–554Drive 359.9 mi
cheapest- Drive from Sioux Falls to Kansas Citycar 359.9 mi
5h 48m$62–89Bus
- Take the bus from Sioux Falls to Kansas Citybus Jefferson Lines 706
9h 25m$96–142Fly to Columbia Regional Airport
- Fly from Sioux Falls (FSD) to Columbia Regional Airport (COU)plane FSD - COU
6h 22m$126–476Fly to Kansas City
- Fly from Sioux Falls (FSD) to Kansas City (MCI)plane FSD - MCI
6h 43m$102–652Fly to Springfield-Branson National Airport
- Fly from Sioux Falls (FSD) to Springfield-Branson National Airport (SGF)plane FSD - SGF
6h 12m$98–452
Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Sioux Falls to Missouri is to drive which costs $60 - $90 and takes 5h 48m.
The fastest way to get from Sioux Falls to Missouri is to fly which takes 5h 35m and costs $95 - $600.
No, there is no direct bus from Sioux Falls to Missouri. However, there are services departing from The Bus Stop and arriving at Kansas City via Sioux Falls. The journey, including transfers, takes approximately 9h 25m.
The distance between Sioux Falls and Missouri is 490 miles. The road distance is 362 miles.
The best way to get from Sioux Falls to Missouri without a car is to bus which takes 9h 25m and costs $95 - $150.
It takes approximately 5h 35m to get from Sioux Falls to Missouri, including transfers.
Sioux Falls to Missouri bus services, operated by Jefferson Lines, depart from Sioux Falls station.
The best way to get from Sioux Falls to Missouri is to fly which takes 5h 35m and costs $95 - $600. Alternatively, you can bus, which costs $95 - $150 and takes 9h 25m.
Sioux Falls to Missouri bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Sioux Falls to Missouri is 362 miles. It takes approximately 5h 48m to drive from Sioux Falls to Missouri.
What companies run services between Sioux Falls, SD, USA and Missouri, USA?
Delta, American Airlines, and United Airlines fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Jefferson Lines operates a bus from Sioux Falls to Kansas City once daily. Tickets cost $95–140 and the journey takes 8h 10m.
- Website
- united.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $140–700
Flights from Sioux Falls to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $75–410
Flights from Sioux Falls to Columbia Regional Airport via Denver
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $95–480
Flights from Sioux Falls to Kansas City via Denver
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $140–750
Flights from Sioux Falls to Kansas City via Chicago O'Hare
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $130–700
Flights from Sioux Falls to Springfield-Branson National Airport via Denver
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- $95–470
Flights from Sioux Falls to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $80–430
- Website
- aa.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $140–700
Flights from Sioux Falls to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $100–490
Flights from Sioux Falls to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $75–410
Flights from Sioux Falls to Kansas City via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $130–700
Flights from Sioux Falls to Kansas City via Dallas/Ft.Worth
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $160–800
Flights from Sioux Falls to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $80–430
Flights from Sioux Falls to Springfield-Branson National Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $95–470
- Website
- delta.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $95–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $150–750
Flights from Sioux Falls to Kansas City via Minneapolis
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $100–650
Flights from Sioux Falls to Kansas City via Atlanta
- Ave. Duration
- 6h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–950
Flights from Sioux Falls to Springfield-Branson National Airport via Atlanta
- Ave. Duration
- 9h 16m
- When
- Every day
- Estimated price
- $120–550
- Website
- allegiantair.com
Flights from Sioux Falls to Springfield-Branson National Airport via Phoenix esa Gateway
- Ave. Duration
- 7h 51m
- When
- Sunday
- Estimated price
- $150–650
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Kansas City
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
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