Rome2Rio

How to get fromSioux Falls to Myrtle Beachby plane, bus (Greyhound, Flixbus), car, bus, bus (Flixbus, Greyhound), or train

Find Transport to Myrtle Beach

See all options

There are 7 ways to get from Sioux Falls to Myrtle Beach by plane, bus (Greyhound, Flixbus), car, bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Myrtle Beach

    best
    1. Fly from Sioux Falls (FSD) to Myrtle Beach (MYR)plane plane FSD - MYR
    6h 13m
    $108–446

  2. Bus via Minneapolis

    1. Take the bus from Sioux Falls to Minneapolisbus bus
    2. Take the bus from Minneapolis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    42h 15m
    $302–582

  3. Drive 1,449 mi

    1. Drive from Sioux Falls to Myrtle Beachcar car 1,449 mi
    25h 44m
    $265–382

  4. Fly to Wilmington International Airport, bus

    1. Fly from Sioux Falls (FSD) to Wilmington International Airport (ILM)plane plane FSD - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    9h 5m
    $138–594

  5. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    42h 20m
    $296–566

  6. Bus via Saint Cloud

    1. Take the bus from Sioux Falls to St. Cloudbus bus
    2. Take the bus from Saint Cloud to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    45h 50m
    $312–572

  7. Bus, train

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    4. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train
    5. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    46h 49m
    $412–806

Sioux Falls (FSD) to Myrtle Beach (MYR) flights

Calendar25Weekly Planes
Duration6h 56mAverage Duration
Ticket$96Cheapest Price
See schedules

Questions & Answers

Map of how to get from Sioux Falls to Myrtle Beach.ExpandLaunch map view
  • Distance: 1,181.7 mi
  • Duration: 6h 13m

What companies run services between Sioux Falls, SD, USA and Myrtle Beach, SC, USA?

Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to Myrtle Beach (MYR) 4 times a day. Alternatively, you can take a bus from The Bus Stop to Myrtle Beach Bus Station via Maple/Career NE corner, Sioux Falls, Minneapolis Bus Station, Chicago Bus Station, and Atlanta Bus Station in around 42h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers