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How to get fromSioux Falls to Panama City Beachby plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Sioux Falls to Panama City Beach by plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from Sioux Falls (FSD) to Northwest Florida Beaches International Airport (ECP)plane plane FSD - ECP
    7h 1m
    $152–556

  2. Fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Sioux Falls (FSD) to Destin–Fort Walton Beach Airport (VPS)plane plane FSD - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    7h 27m
    $112–498

  3. Bus via Shreveport

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City to Texarkanabus bus
    3. Take the bus from Texarkana to Shreveport Bus Stationbus bus
    4. Take the bus from Shreveport Bus Station to Baton Rouge Bus Stationbus bus
    5. Take the bus from Baton Rouge Bus Station to Panama City Beach Bus Stationbus bus
    35h 54m
    $312–520

  4. Drive 1,298.9 mi

    1. Drive from Sioux Falls to Panama City Beachcar car 1,298.9 mi
    23h
    $238–343

  5. Fly to Dothan Regional Airport, drive

    1. Fly from Sioux Falls (FSD) to Dothan Regional Airport (DHN)plane plane FSD - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama City Beachcar car
    8h 48m
    $118–498

  6. Fly to Pensacola International Airport, bus

    1. Fly from Sioux Falls (FSD) to Pensacola International Airport (PNS)plane plane FSD - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    10h
    $120–482

  7. Fly to Tallahassee, bus

    1. Fly from Sioux Falls (FSD) to Tallahassee (TLH)plane plane FSD - TLH
    2. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    9h 29m
    $178–722

  8. Bus

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    5. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    37h 29m
    $276–498

  9. Bus #2

    1. Take the bus from Sioux Falls to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    4. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    5. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    40h 19m
    $284–508

Sioux Falls (FSD) to Northwest Florida Beaches International Airport (ECP) flights

Calendar30Weekly Planes
Duration7h 3mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Panama City Beach.ExpandLaunch map view
  • Distance: 1,115 mi
  • Duration: 7h 1m

What companies run services between Sioux Falls, SD, USA and Panama City Beach, FL, USA?

Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to Northwest Florida Beaches International Airport (ECP) 4 times a day. Alternatively, you can take a bus from The Bus Stop to Panama City Beach via Maple/Career NE corner, Sioux Falls, Kansas City, Texarkana, Shreveport Bus Station, Baton Rouge Bus Station, and Panama City Beach Bus Station in around 35h 54m.

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