There are 4 ways to get from Sioux Falls to Saint Charles by plane, bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL)plane FSD - STL
6h 9m$116–576Drive 587.5 mi
cheapest- Drive from Sioux Falls to Saint Charlescar 587.5 mi
9h 40m$101–145Bus
- Take the bus from Sioux Falls to Kansas Citybus Jefferson Lines 706
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0180s / ...
16h 32m$160–234Bus, train
- Take the bus from Sioux Falls to Kansas Citybus Jefferson Lines 706
- Take the train from Kansas City to St. Louistrain Missouri River Runner / ...
17h 44m$274–416
Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Sioux Falls to Saint Charles is to drive which costs $100 - $150 and takes 9h 40m.
The fastest way to get from Sioux Falls to Saint Charles is to fly which takes 6h 9m and costs $110 - $600.
No, there is no direct bus from Sioux Falls to Saint Charles. However, there are services departing from The Bus Stop and arriving at 4375 Rider Trail North Sb via Sioux Falls, Kansas City Bus Station, Civic Center Transit Center and North Hanley Transit Center. The journey, including transfers, takes approximately 16h 32m.
The distance between Sioux Falls and Saint Charles is 496 miles. The road distance is 590.9 miles.
The best way to get from Sioux Falls to Saint Charles without a car is to bus which takes 16h 32m and costs $160 - $240.
It takes approximately 6h 9m to get from Sioux Falls to Saint Charles, including transfers.
Sioux Falls to Saint Charles bus services, operated by Jefferson Lines, depart from Sioux Falls station.
The best way to get from Sioux Falls to Saint Charles is to fly which takes 6h 9m and costs $110 - $600. Alternatively, you can bus, which costs $160 - $240 and takes 16h 32m.
Sioux Falls to Saint Charles bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Sioux Falls to Saint Charles is 591 miles. It takes approximately 9h 40m to drive from Sioux Falls to Saint Charles.
What companies run services between Sioux Falls, SD, USA and Saint Charles, MO, USA?
Delta, American Airlines, and United Airlines fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from The Bus Stop to Saint Charles via Maple/Career NE corner, Sioux Falls, Kansas City, Kansas City Bus Station, St Louis Bus Station, Civic Center Transit Center, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 16h 32m.
- Website
- united.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $140–700
- Website
- aa.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $95–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Kansas City
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
Bus from Sioux Falls to Kansas City
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
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Booking & Getting There
There are 235+ hotels available in Saint Charles.