There are 4 ways to get from Sioux Falls to St. Louis by plane, bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL)plane FSD - STL
5h 52m$100–554Bus
- Take the bus from Sioux Falls to Kansas Citybus Jefferson Lines 706
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0180s / ...
14h 25m$132–206Drive 607.3 mi
- Drive from Sioux Falls to St. Louiscar 607.3 mi
10h$111–161Bus, train
- Take the bus from Sioux Falls to Kansas Citybus Jefferson Lines 706
- Take the train from Kansas City to St. Louistrain Missouri River Runner / ...
16h 45m$172–312
Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Sioux Falls to St. Louis is to drive which costs $110 - $160 and takes 10h.
The fastest way to get from Sioux Falls to St. Louis is to fly which takes 5h 52m and costs $95 - $600.
No, there is no direct bus from Sioux Falls to St. Louis station. However, there are services departing from The Bus Stop and arriving at St Louis Bus Station via Sioux Falls and Kansas City Bus Station. The journey, including transfers, takes approximately 14h 25m.
The distance between Sioux Falls and St. Louis is 490 miles. The road distance is 610.8 miles.
The best way to get from Sioux Falls to St. Louis without a car is to bus which takes 14h 25m and costs $130 - $210.
It takes approximately 5h 52m to get from Sioux Falls to St. Louis, including transfers.
Sioux Falls to St. Louis bus services, operated by Jefferson Lines, depart from Sioux Falls station.
The best way to get from Sioux Falls to St. Louis is to fly which takes 5h 52m and costs $95 - $600. Alternatively, you can bus, which costs $130 - $210 and takes 14h 25m.
Sioux Falls to St. Louis bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Sioux Falls to St. Louis is 611 miles. It takes approximately 10h to drive from Sioux Falls to St. Louis.
What companies run services between Sioux Falls, SD, USA and St. Louis, MO, USA?
Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from The Bus Stop to St Louis Bus Station via Maple/Career NE corner, Sioux Falls, Kansas City, and Kansas City Bus Station in around 14h 25m.
- Website
- united.com
Flights from Sioux Falls to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $100–550
Flights from Sioux Falls to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $75–170
- Website
- Amtrak
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Kansas City
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
Bus from Sioux Falls to Kansas City
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- Jefferson Lines
- Adult
- $95–140
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