Rome2Rio

How to get fromSioux Falls to St. Louisby plane, bus (Greyhound), car, bus, or train

Find Transport to St. Louis

See all options

There are 4 ways to get from Sioux Falls to St. Louis by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL)plane plane FSD - STL
    5h 57m
    $104–554

  2. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Des Moinesbus bus
    3. Take the bus from Des Moines to St Louis Bus Stationbus bus
    17h 25m
    $138–252

  3. Drive 607.3 mi

    1. Drive from Sioux Falls to St. Louiscar car 607.3 mi
    10h
    $111–161

  4. Bus, train

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha to Kansas Citybus bus
    3. Take the train from Kansas City to St. Louistrain train
    17h 30m
    $196–346

Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) flights

Calendar116Weekly Planes
Duration5h 33mAverage Duration
Ticket$104Cheapest Price
See schedules

Questions & Answers

Map of how to get from Sioux Falls to St. Louis.ExpandLaunch map view
  • Distance: 487.5 mi
  • Duration: 5h 57m

What companies run services between Sioux Falls, SD, USA and St. Louis, MO, USA?

Delta, United Airlines, and American Airlines fly from Sioux Falls (FSD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from The Bus Stop to St Louis Bus Station via Maple/Career NE corner, Sioux Falls, Omaha, NE, and Des Moines in around 17h 25m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers