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How to get fromSioux Falls to Tupeloby plane, car, bus (Greyhound), bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Sioux Falls to Tupelo by plane, car, bus (Greyhound), bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Sioux Falls (FSD) to Golden Triangle Regional Airport (GTR)plane plane FSD - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    9h 57m
    $122–508

  2. Fly to Tupelo Regional Airport

    cheapest
    1. Fly from Sioux Falls (FSD) to Tupelo Regional Airport (TUP)plane plane FSD - TUP
    7h 17m
    $116–490

  3. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha to Kansas Citybus bus
    3. Take the bus from Kansas City to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    23h 59m
    $244–360

  4. Drive 905.3 mi

    1. Drive from Sioux Falls to Tupelocar car 905.3 mi
    15h 42m
    $166–239

  5. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Sioux Falls (FSD) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane FSD - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    9h 11m
    $134–586

  6. Fly to Memphis, bus

    1. Fly from Sioux Falls (FSD) to Memphis (MEM)plane plane FSD - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    10h 3m
    $180–796

  7. Bus via St. Louis

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Des Moinesbus bus
    3. Take the bus from Des Moines to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus
    5. Take the bus from Memphis Bus Station to Tupelobus bus
    25h 54m
    $210–386

Sioux Falls (FSD) to Golden Triangle Regional Airport (GTR) flights

Calendar29Weekly Planes
Duration8h 6mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to Tupelo.ExpandLaunch map view
  • Distance: 891.2 mi
  • Duration: 9h 57m

What companies run services between Sioux Falls, SD, USA and Tupelo, MS, USA?

You can take a bus from The Bus Stop to Tupelo via Maple/Career NE corner, Sioux Falls, Omaha, Kansas City, Memphis Bus Station, and Tupelo in around 23h 59m. Alternatively, American Airlines, Corporate Flight Management Inc, and two other airlines fly from Sioux Falls (FSD) to Tupelo Regional Airport (TUP) once daily.

Airlines
Bus operators

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