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How to get fromSioux Falls to West Lafayetteby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus, Amtrak)

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There are 8 ways to get from Sioux Falls to West Lafayette by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Purdue University Airport

    best
    1. Fly from Sioux Falls (FSD) to Purdue University Airport (LAF)plane plane FSD - LAF
    7h 27m
    $68–362

  2. Bus

    1. Take the bus from Sioux Falls to Omahabus bus
    2. Take the bus from Omaha, NE to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Lafayette Bus Stopbus bus
    18h 50m
    $140–252

  3. Bus, train via Albert Lea

    1. Take the bus from Sioux Falls to Albert Leabus bus
    2. Take the bus from Albert Lea to St. Paulbus bus
    3. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    19h 38m
    $242–466

  4. Drive 660.8 mi

    1. Drive from Sioux Falls to West Lafayettecar car 660.8 mi
    12h 21m
    $121–175

  5. Fly to Indianapolis, bus

    1. Fly from Sioux Falls (FSD) to Indianapolis (IND)plane plane FSD - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 15m
    $130–592

  6. Fly to Chicago O'Hare International Airport, train

    1. Fly from Sioux Falls (FSD) to Chicago O'Hare International Airport (ORD)plane plane FSD - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 12m
    $84–366

  7. Bus, train

    1. Take the bus from Sioux Falls to Minneapolis-St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    21h 54m
    $244–464

  8. Bus via Saint Cloud

    1. Take the bus from Sioux Falls to St. Cloudbus bus
    2. Take the bus from Saint Cloud to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus
    22h 29m
    $164–272

Sioux Falls (FSD) to Purdue University Airport (LAF) flights

Calendar33Weekly Planes
Duration7h 25mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Sioux Falls to West Lafayette.ExpandLaunch map view
  • Distance: 553.1 mi
  • Duration: 7h 27m

What companies run services between Sioux Falls, SD, USA and West Lafayette, IN, USA?

United Airlines and American Airlines fly from Sioux Falls (FSD) to Purdue University Airport (LAF) 5 times a day. Alternatively, you can take a bus from The Bus Stop to Lafayette Bus Stop via Maple/Career NE corner, Sioux Falls, Omaha, NE, and Chicago Bus Station in around 18h 50m.

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