There are 6 ways to get from Sistine Chapel to Florence by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 64 bus, train
best- Take the bus from Cavalleggeri/Fornaci to Terminibus 64 / ...
- Take the train from Roma Termini to Firenze S.M.N.train Fr
2h 26m€30–88Bus
cheapest- Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...
4h 35m€18–54Drive 275.5 km
- Drive from Sistine Chapel to Florencecar 275.5 km
2h 44m€44–63Train, fly to Florence Peretola Airport
- Take the train from Roma S. Pietro to Roma Trasteveretrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
3h 20m€64–198Train
- Take the train from Roma Termini to Firenze Santa Maria Novellatrain 8134 / ...
2h 57m€32–74Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
3h 52m€51–163
Sistine Chapel to Florence by foot, bus, and train
Questions & Answers
The cheapest way to get from Sistine Chapel to Florence is to bus which costs €18 - €55 and takes 4h 35m.
The fastest way to get from Sistine Chapel to Florence is to line 64 bus and train which takes 2h 26m and costs €29 - €90.
No, there is no direct bus from Sistine Chapel to Florence station. However, there are services departing from Cavalleggeri/Fornaci and arriving at Florence Villa Constanza Bus Station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 35m.
No, there is no direct train from Sistine Chapel to Florence. However, there are services departing from Roma Termini and arriving at Firenze Santa Maria Novella via . The journey, including transfers, takes approximately 2h 57m.
The distance between Sistine Chapel and Florence is 267 km. The road distance is 275.5 km.
The best way to get from Sistine Chapel to Florence without a car is to line 64 bus and train which takes 2h 26m and costs €29 - €90.
It takes approximately 2h 26m to get from Sistine Chapel to Florence, including transfers.
Sistine Chapel to Florence bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Sistine Chapel to Florence train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Sistine Chapel to Florence is to bus which takes 4h 35m and costs €18 - €55. Alternatively, you can train, which costs €30 - €75 and takes 2h 57m.
What companies run services between Sistine Chapel, Vatican City and Florence, Italy?
FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station hourly. Tickets cost €23–40 and the journey takes 3h 15m. Three other operators also service this route. Alternatively, ItaloTreno operates a train from Roma Termini to Firenze Santa Maria Novella every 30 minutes. Tickets cost €30–65 and the journey takes 2h 7m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €60–150
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- €55–110
- Website
- polarair.ru
Flights from Fiumicino International Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 15m
- When
- Thursday
- Estimated price
- €30–420
- Website
- flexflight.dk
Flights from Fiumicino International Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 15m
- When
- Thursday
- Estimated price
- €30–420
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–27
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 35m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Roma S. Pietro to Roma Trastevere
- Ave. Duration
- 6 min
- Frequency
- Every 10 minutes
- Estimated price
- €1
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–60
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- 3 times a day
- Estimated price
- €9–20
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Firenze Santa Maria Novella
- Ave. Duration
- 2h 7m
- Frequency
- Every 30 minutes
- Estimated price
- €30–65
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- 5 times a day
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 46951
- Website
- atac.roma.it
Bus from Cavalleggeri/Fornaci to Termini
- Ave. Duration
- 31 min
- Frequency
- Every 10 minutes
- Estimated price
- €2–9
- Website
- https://www.atac.roma.it/en
- 100-minute intergrated ticket
- €2
- 24-hour ticket
- €9
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €24–45
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- €17–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- autolineemoretti.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 incredible day trips from Florence by train
Read the travel guide
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Sistine Chapel to Florence bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Sistine Chapel to Florence train services, operated by ItaloTreno, arrive at Firenze Santa Maria Novella station.
Yes, the driving distance between Sistine Chapel to Florence is 275 km. It takes approximately 2h 44m to drive from Sistine Chapel to Florence.
There are 8489+ hotels available in Florence.