There are 7 ways to get from Sistine Chapel to Florence by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma S. Pietro to Roma Tiburtinatrain Re / ...
- Take the train from Roma Tiburtina to Firenze Santa Maria Novellatrain 8134 / ...
2h 27m€31–52Line 62 bus, bus
cheapest- Take the bus from Cavalleggeri/Fornaci to Roma, Autostazione Tiburtinabus 62
- Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...
4h 29m€16–48Drive 275.5 km
- Drive from Sistine Chapel to Florencecar 275.5 km
2h 44m€50–72Train, fly to Florence Peretola Airport
- Take the train from Roma S. Pietro to Roma Trasteveretrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
3h 23m€64–207Line 64 bus, train
- Take the bus from Cavalleggeri/Fornaci to Terminibus 64 / ...
- Take the train from Roma Termini to Firenze S.M.N.train Fr
2h 33m€30–68Line 64 bus, train via Sistine Chapel
- Take the bus from Cavalleggeri/Fornaci to Terminibus 64 / ...
- Take the train from Roma Termini to Florence Santa Maria Novellatrain 9928 / ...
3h 20m€32–58Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
4h 24m€67–206
Sistine Chapel to Florence by foot and bus
Comparing Your Travel Options
The cheapest way to get from Sistine Chapel to Florence is to line 62 bus and bus which costs €15 - €50 and takes 4h 29m.
The fastest way to get from Sistine Chapel to Florence is to train which takes 2h 27m and costs €30 - €55.
No, there is no direct bus from Sistine Chapel to Florence station. However, there are services departing from Cavalleggeri/Fornaci and arriving at Florence Villa Constanza Bus Station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 4h 29m.
No, there is no direct train from Sistine Chapel to Florence. However, there are services departing from Roma S. Pietro and arriving at Firenze Santa Maria Novella via Roma Tiburtina. The journey, including transfers, takes approximately 2h 27m.
The distance between Sistine Chapel and Florence is 270 km. The road distance is 275.5 km.
The best way to get from Sistine Chapel to Florence without a car is to train which takes 2h 27m and costs €30 - €55.
It takes approximately 2h 27m to get from Sistine Chapel to Florence, including transfers.
Sistine Chapel to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Cavalleggeri/Fornaci station.
Sistine Chapel to Florence train services, operated by Trenitalia, depart from Roma S. Pietro station.
The best way to get from Sistine Chapel to Florence is to train which takes 2h 27m and costs €30 - €55. Alternatively, you can line 62 bus and bus, which costs €15 - €50 and takes 4h 29m.
What companies run services between Sistine Chapel, Vatican City and Florence, Italy?
You can take a vehicle from Sistine Chapel to Firenze Santa Maria Novella via Roma S. Pietro and Roma Tiburtina in around 2h 27m. Alternatively, you can take a vehicle from Sistine Chapel to Florence Villa Constanza Bus Station via Cavalleggeri/Fornaci and Roma, Autostazione Tiburtina in around 4h 29m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €60–150
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €55–140
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma S. Pietro to Roma Tiburtina
- Ave. Duration
- 29 min
- Frequency
- Hourly
- Estimated price
- €1–2
- Website
- Trenitalia
Train from Roma S. Pietro to Roma Trastevere
- Ave. Duration
- 6 min
- Frequency
- Every 30 minutes
- Estimated price
- €1
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Tiburtina to Firenze Santa Maria Novella
- Ave. Duration
- 1h 27m
- Frequency
- Every 30 minutes
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Roma Termini to Florence Santa Maria Novella
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 41 min
- Frequency
- 5 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
- Phone
- +39 06 46951
- Website
- Atac Roma
Bus from Cavalleggeri/Fornaci to Roma, Autostazione Tiburtina
- Ave. Duration
- 53 min
- Frequency
- Every 20 minutes
- Estimated price
- €2–9
- Website
- Atac Roma
- 100-minute intergrated ticket
- €2
- 24-hour ticket
- €9
Bus from Cavalleggeri/Fornaci to Termini
- Ave. Duration
- 29 min
- Frequency
- Every 10 minutes
- Estimated price
- €2–9
- Website
- Atac Roma
- 100-minute intergrated ticket
- €2
- 24-hour ticket
- €9
Bus from Cavalleggeri/Fornaci to Termini
- Ave. Duration
- 29 min
- Frequency
- Every 10 minutes
- Estimated price
- €2–9
- Website
- Atac Roma
- 100-minute intergrated ticket
- €2
- 24-hour ticket
- €9
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Every 30 minutes
- Estimated price
- €24–40
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- €14–25
- Website
- Itabus S.p.A.
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- €22–40
- Website
- BlaBlaCar Bus
- Phone
- +39 0972 24590
- [email protected]
- Website
- autolineemoretti.it
Bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- autolineemoretti.it
Want to know more about travelling around Italy
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Booking & Getting There
Sistine Chapel to Florence bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Roma, Autostazione Tiburtina station.
Sistine Chapel to Florence train services, operated by Trenitalia, arrive at Roma Tiburtina station.
Yes, the driving distance between Sistine Chapel to Florence is 275 km. It takes approximately 2h 44m to drive from Sistine Chapel to Florence.
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