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How to get fromSistine Chapel to Pisaby train (Trenitalia), bus, car, plane, or train

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There are 9 ways to get from Sistine Chapel to Pisa by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Roma S. Pietro to Pisa Centraletrain train 4136 / ...
    3h 57m
    €30–70

  2. Bus

    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N548 / ...
    7h 33m
    €30–58

  3. Drive 323.4 km

    1. Drive from Sistine Chapel to Pisacar car 323.4 km
    3h 45m
    €51–74

  4. Fly Fiumicino International Airport to Florence Peretola Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    4h 48m
    €73–204

  5. Train via Roma Tiburtina (Trenitalia)

    1. Take the train from Roma Tiburtina to Pisa Centraletrain train Fa
    3h 58m
    €47–102

  6. Fly Fiumicino International Airport to Pisa International Airport

    1. Fly from Fiumicino International Airport (FCO) to Pisa International Airport (PSA)plane plane FCO - PSA
    5h 3m
    €47–186

  7. Fly Roma Ciampino Airport to Pisa International Airport

    1. Fly from Roma Ciampino Airport (CIA) to Pisa International Airport (PSA)plane plane CIA - PSA
    5h 55m
    €58–302

  8. Fly Fiumicino International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 19m
    €60–179

  9. Fly Fiumicino International Airport to Genoa Cristoforo Colombo Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane plane FCO - GOA
    2. Take the train from Genova P.Za Principe to Pisa Centraletrain train
    5h 59m
    €60–208

Sistine Chapel to Pisa by foot and train (Trenitalia)

Calendar100Weekly Services
Duration3h 57mAverage Duration
Ticket€30Cheapest Price
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Questions & Answers

Map of how to get from Sistine Chapel to Pisa.ExpandLaunch map view
  • Distance: 320.7 km
  • Duration: 3h 57m

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

Trenitalia operates a train from Roma S. Pietro to Pisa Centrale hourly. Tickets cost €35–65 and the journey takes 3h 43m. Trenitalia Intercity also services this route 4 times a week. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €29–50 and the journey takes 5h 30m.

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