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How to get fromSistine Chapel to Pisaby train (Trenitalia), bus, car, plane, or train

Find Transport to Pisa

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There are 7 ways to get from Sistine Chapel to Pisa by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Roma Termini to Pisa Centraletrain train Fa / ...
    3h 50m
    €36–88

  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N1508 / ...
    6h 34m
    €30–54

  3. Drive  323.4 km

    1. Drive from Sistine Chapel to Pisacar car 323.4 km
    3h 45m
    €53–76

  4. Fly to Florence Peretola Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    4h 52m
    €73–220

  5. Bus via Anagnina

    1. Take the bus from Roma - Via Vincenzo Giudice to Pisabus bus
    8h 1m
    €32–66

  6. Fly to Pisa International Airport

    1. Fly from Fiumicino International Airport (FCO) to Pisa International Airport (PSA)plane plane FCO - PSA
    5h 20m
    €57–205

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 45m
    €70–220

Sistine Chapel to Pisa by foot, bus, and train (Trenitalia)

Calendar105Weekly Services
Duration3h 50mAverage Duration
Ticket€36Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sistine Chapel to Pisa.ExpandLaunch map view
  • Distance: 342.3 km
  • Duration: 3h 50m

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

Trenitalia Frecce operates a train from Roma Termini to Pisa Centrale every 4 hours. Tickets cost €45–80 and the journey takes 2h 27m. Two other operators also service this route. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €29–45 and the journey takes 4h 35m.

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