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How to get fromSkaneateles to Chicagoby bus, plane, train (Amtrak), bus (Greyhound), car, or train

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There are 9 ways to get from Skaneateles to Chicago by bus, plane, train (Amtrak), bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from State St & Academy St to C22bus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    6h 22m
    $74–411

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    15h 27m
    $222–456

  3. Bus (Greyhound)

    1. Take the bus from Syracuse Bus Station to Cleveland Bus Stationbus bus Greyhound US0171
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    17h 30m
    $107–226

  4. Drive 659 mi

    1. Drive from Skaneateles to Chicagocar car 659 mi
    11h 24m
    $121–174

  5. Fly Syracuse Hancock International Airport to Chicago Midway International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW)plane plane SYR - MDW
    8h 1m
    $89–481

  6. Train to Rochester, fly to Chicago Midway International Airport

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    7h 7m
    $119–624

  7. Train to Rochester, fly to Chicago O'Hare International Airport

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    7h 37m
    $109–564

  8. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    8h 22m
    $191–541

  9. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    8h 44m
    $181–411

Skaneateles to Chicago by bus and train (Amtrak)

Calendar14Weekly Services
Duration15h 27mAverage Duration
Ticket$222Cheapest Price
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Questions & Answers

Map of how to get from Skaneateles to Chicago.ExpandLaunch map view
  • Distance: 658.8 mi
  • Duration: 6h 22m

What companies run services between Skaneateles, NY, USA and Chicago, IL, USA?

Amtrak operates a train from Syracuse Regional Transportation Center to Chicago Union Station twice daily. Tickets cost $220–440 and the journey takes 13h 7m. Alternatively, you can take a bus from State St & Academy St to Chicago Bus Station via C22, B8, Syracuse Bus Station, and Cleveland Bus Station in around 17h 30m.

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