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How to get fromSophia Antipolis to Lyonby train (TGV, Trenitalia), bus, car, plane, or train (TGV)

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There are 6 ways to get from Sophia Antipolis to Lyon by train (TGV, Trenitalia), bus, car, plane, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Marseille

    best
    1. Take the train from Cannes to Marseille St Charlestrain train Tgv
    2. Take the train from Marseille St Charles to Lyon Part Dieutrain train Tgv
    4h 18m
    €110–238

  2. Bus via Nice - Airport Bus Station Terminal 1

    cheapest
    1. Take the bus from Nice - Airport Bus Station Terminal 1 to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    7h 47m
    €32–62

  3. Drive  398.3 km

    1. Drive from Sophia Antipolis to Lyoncar car 398.3 km
    5h 27m
    €64–92

  4. Fly

    1. Fly from Nice Côte D'Azur International Airport (NCE) to Lyon–Saint Exupéry Airport (LYS)plane plane NCE - LYS
    3h 30m
    €98–278

  5. Train (TGV)

    1. Take the train from Cannes to Lyon Part Dieutrain train Tgv
    5h 53m
    €105–165

  6. Bus

    1. Take the bus from Nice to Lyonbus bus N1719 / ...
    9h 9m
    €45–76

Sophia Antipolis to Lyon by bus

Calendar71Weekly Buses
Duration7h 47mAverage Duration
Ticket€32Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sophia Antipolis to Lyon.ExpandLaunch map view
  • Distance: 523.7 km
  • Duration: 4h 18m

What companies run services between Sophia Antipolis, France and Lyon, France?

You can take a vehicle from Sophia Antipolis to Lyon Part Dieu via Cannes and Marseille St Charles in around 4h 18m. Alternatively, BlaBlaCar Bus operates a bus from Nice - Airport Bus Station Terminal 1 to Lyon - Gerland Bus Station every 3 hours. Tickets cost €30–60 and the journey takes 6h 20m. FlixBus also services this route twice daily.

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