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How to get fromSouth Bend to Depewby plane, train (Amtrak), bus, car, or bus (Greyhound)

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There are 5 ways to get from South Bend to Depew by plane, train (Amtrak), bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from South Bend (SBN) to Buffalo Niagara International Airport (BUF)plane plane SBN - BUF
    4h 10m
    $141–738

  2. Bus

    cheapest
    1. Take the bus from South Bend, IN to Clevelandbus bus Chicago
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    11h 13m
    $45–128

  3. Train (Amtrak)

    1. Take the train from South Bend Station to Buffalo Depew Stationtrain train Lake Shore Limited
    8h 58m
    $154–302

  4. Drive 447.4 mi

    1. Drive from South Bend to Depewcar car 447.4 mi
    7h 37m
    $82–118

  5. Bus via Brook Park (Greyhound)

    1. Take the bus from South Bend Transpo to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    11h 43m
    $73–137

South Bend to Depew by bus

Calendar7Weekly Buses
Duration11h 13mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from South Bend to Depew.ExpandLaunch map view
  • Distance: 404.6 mi
  • Duration: 4h 10m

What companies run services between South Bend, IN, USA and Depew, NY, USA?

Delta, United Airlines, and American Airlines fly from South Bend (SBN) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, Amtrak operates a train from South Bend Station to Buffalo Depew Station twice daily. Tickets cost $140–300 and the journey takes 8h 54m.

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