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How to get fromSouth Bend to Des Moinesby plane, bus (Greyhound, Flixbus), car, train, bus, or bus (Amtrak, Greyhound)

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There are 8 ways to get from South Bend to Des Moines by plane, bus (Greyhound, Flixbus), car, train, bus, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from South Bend

    best
    1. Fly from South Bend (SBN) to Des Moines (DSM)plane plane SBN - DSM
    4h 1m
    $82–380

  2. Bus

    cheapest
    1. Take the bus from South Bend, IN to Chicagobus bus Columbus / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    9h 15m
    $64–107

  3. Drive  404.8 mi

    1. Drive from South Bend to Des Moinescar car 404.8 mi
    6h 59m
    $74–107

  4. Train to Chicago O'Hare International Airport, fly

    1. Take the train from South Bend Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    5h 41m
    $83–358

  5. Train to Chicago Midway International Airport, fly

    1. Take the train from South Bend Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    5h 36m
    $95–465

  6. Train, bus

    1. Take the train from South Bend Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    9h 44m
    $70–132

  7. Bus via South Bend Station

    1. Take the bus from South Bend Station to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    9h 44m
    $71–115

  8. Train, bus via Galesburg

    1. Take the train from South Bend Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    11h 36m
    $85–197

South Bend to Des Moines by bus

Calendar19Weekly Buses
Duration9h 15mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from South Bend to Des Moines.ExpandLaunch map view
  • Distance: 389.4 mi
  • Duration: 4h 1m

What companies run services between South Bend, IN, USA and Des Moines, IA, USA?

United Airlines, Delta, and American Airlines fly from South Bend (SBN) to Des Moines (DSM) hourly. Alternatively, you can take a bus from South Bend, IN to Des Moines via Chicago Bus Station in around 9h 15m.

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