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How to get fromSouth Bend to Sikestonby plane, car, train, bus, taxi, or bus (Greyhound, Flixbus)

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There are 6 ways to get from South Bend to Sikeston by plane, car, train, bus, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly South Bend to Barkley Regional Airport, drive

    best
    1. Fly from South Bend (SBN) to Barkley Regional Airport (PAH)plane plane SBN - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    6h 24m
    $79–372

  2. Train, bus

    1. Take the train from South Bend Station to Chicago Union Stationtrain train Lake Shore Limited / ...
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    11h 29m
    $160–219

  3. Train, drive (Amtrak)

    1. Take the train from South Bend Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    12h 21m
    $278–440

  4. Drive  451.9 mi

    1. Drive from South Bend to Sikestoncar car 451.9 mi
    7h 38m
    $83–120

  5. Train to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport, taxi

    1. Take the train from South Bend Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    6h 12m
    $231–589

  6. Bus

    1. Take the bus from South Bend to Chicagobus bus Bsb 21 / ...
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    11h 46m
    $126–166

South Bend (SBN) to Barkley Regional Airport (PAH) flights

Calendar28Weekly Planes
Duration7h 1mAverage Duration
Ticket$56Cheapest Price
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Comparing Your Travel Options

Map of how to get from South Bend to Sikeston.ExpandLaunch map view
  • Distance: 405.1 mi
  • Duration: 6h 24m

What companies run services between South Bend, IN, USA and Sikeston, MO, USA?

You can take a bus from South Bend to Sikeston via Chicago, Harrison & Jefferson, Cicero & 24th Place Terminal, Tornado Bus Co - Chicago, and Flying J - Matthews in around 11h 46m.

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