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How to get fromSouth Carolina to Des Moinesby taxi, plane, train, bus, or car

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There are 8 ways to get from South Carolina to Des Moines by taxi, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Charlotte Douglas International Airport, fly

    best
    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Des Moines (DSM)plane plane CLT - DSM
    3h 8m
    $268–967

  2. Fly from Charleston International Airport

    cheapest
    1. Fly from Charleston International Airport (CHS) to Des Moines (DSM)plane plane CHS - DSM
    6h 39m
    $171–775

  3. Train, bus

    1. Take the train from Charleston Amtrak Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    38h 41m
    $511–1,056

  4. Drive, bus, taxi, train via Atlanta

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Fayetteville Amtrak Stationtrain train
    5. Take the bus from Fayetteville Bus Station to Atlanta Bus Stationbus bus
    6. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    7. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    40h 27m

  5. Drive 1,160.5 mi

    1. Drive from Charleston to Des Moinescar car 1,160.5 mi
    20h 43m
    $212–306

  6. Fly from Greenville–Spartanburg International Airport

    1. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    5h 9m
    $238–969

  7. Fly from Columbia

    1. Fly from Columbia (CAE) to Des Moines (DSM)plane plane CAE - DSM
    5h 58m
    $358–1,722

  8. Drive, bus, taxi, train

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Chicago Union Stationtrain train
    5. Take the bus from Chicago Bus Station to Des Moinesbus bus
    43h 30m

Charlotte Douglas International Airport (CLT) to Des Moines (DSM) flights

Calendar82Weekly Planes
Duration4h 8mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Des Moines.ExpandLaunch map view
  • Distance: 847.1 mi
  • Duration: 3h 8m

What companies run services between South Carolina, USA and Des Moines, IA, USA?

United Airlines, American Airlines, and Delta fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) hourly.

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