There are 9 ways to get from South Carolina to Destin by plane, bus, taxi, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Greenville–Spartanburg International Airport to Destin–Fort Walton Beach Airport
best- Fly from Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS)plane GSP - VPS
4h 39m$136–443Drive 486 mi
cheapest- Drive from Charleston to Destincar 486 mi
9h 50m$84–120Bus, taxi
- Take the bus from Charleston Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to La Grange Bus Stationbus
- Take the bus from La Grange Bus Station to Mobilebus
- Take the bus from Loxley to Crestviewbus
- Take the taxi from Crestview to Destintaxi
23h 52m$285–396Taxi to Charlotte Douglas International Airport, fly to Destin–Fort Walton Beach Airport
- Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi
- Fly from Charlotte Douglas International Airport (CLT) to Destin–Fort Walton Beach Airport (VPS)plane CLT - VPS
2h 55m$186–541Taxi to Charlotte Douglas International Airport, fly to Northwest Florida Beaches International Airport, taxi
- Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi
- Fly from Charlotte Douglas International Airport (CLT) to Northwest Florida Beaches International Airport (ECP)plane CLT - ECP
- Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi
3h 34m$281–666Taxi to Charlotte Douglas International Airport, fly to Pensacola International Airport, taxi
- Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi
- Fly from Charlotte Douglas International Airport (CLT) to Pensacola International Airport (PNS)plane CLT - PNS
- Take the taxi from Pensacola-Airport-PNS to Destintaxi
3h 39m$256–606Fly Columbia to Destin–Fort Walton Beach Airport
- Fly from Columbia (CAE) to Destin–Fort Walton Beach Airport (VPS)plane CAE - VPS
5h 40m$96–406Fly Charleston International Airport to Destin–Fort Walton Beach Airport
- Fly from Charleston International Airport (CHS) to Destin–Fort Walton Beach Airport (VPS)plane CHS - VPS
6h 3m$114–469Drive, bus, taxi, train
- Drive from Charleston to Sonic at Walmartcar
- Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus 302
- Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi
- Take the train from Savannah Station to Jacksonvilletrain
- Take the bus from Jacksonville to Mobile Bus Stationbus
- Take the bus from Mobile to Crestviewbus
- Take the taxi from Crestview to Destintaxi
24h 19m
Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS) flights
Comparing Your Travel Options
The cheapest way to get from South Carolina to Destin is to drive which costs $80 - $120 and takes 9h 50m.
The fastest way to get from South Carolina to Destin is to taxi and fly which takes 2h 55m and costs $180 - $550.
The distance between South Carolina and Destin is 427 miles. The road distance is 488.8 miles.
The best way to get from South Carolina to Destin without a car is to bus and taxi which takes 23h 52m and costs $280 - $400.
It takes approximately 4h 39m to get from South Carolina to Destin, including transfers.
Destin is 1h behind South Carolina. It is currently 11:53 PM in South Carolina and 10:53 PM in Destin.
Yes, the driving distance between South Carolina to Destin is 489 miles. It takes approximately 9h 50m to drive from South Carolina to Destin.
There are 7196+ hotels available in Destin.
What companies run services between South Carolina, USA and Destin, FL, USA?
Delta, Southwest Airlines, and American Airlines fly from Greenville–Spartanburg International Airport (GSP) to Destin–Fort Walton Beach Airport (VPS) every 3 hours.
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $55–340
Flights from Charlotte Douglas International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $65–390
Flights from Charlotte Douglas International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $65–390
Flights from Charlotte Douglas International Airport to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $55–350
Flights from Columbia to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $55–350
Flights from Charleston International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $70–410
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Destin–Fort Walton Beach Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $60–370
Flights from Charlotte Douglas International Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $65–390
Flights from Charlotte Douglas International Airport to Northwest Florida Beaches International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $60–390
Flights from Charlotte Douglas International Airport to Pensacola International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $55–350
Flights from Columbia to Destin–Fort Walton Beach Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $60–370
Flights from Columbia to Destin–Fort Walton Beach Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $120–550
Flights from Columbia to Destin–Fort Walton Beach Airport via Reagan Washington
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $100–490
Flights from Charleston International Airport to Destin–Fort Walton Beach Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $75–440
- Website
- southwest.com
Flights from Greenville–Spartanburg International Airport to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–390
Flights from Charlotte Douglas International Airport to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $80–440
Flights from Charlotte Douglas International Airport to Northwest Florida Beaches International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $80–440
Flights from Charlotte Douglas International Airport to Pensacola International Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $70–390
Flights from Charleston International Airport to Destin–Fort Walton Beach Airport via Nashville
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $90–480
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Savannah Station to Jacksonville
- Ave. Duration
- 2h 29m
- Frequency
- Twice daily
- Estimated price
- $80–130
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
Bus from Atlanta Bus Station to La Grange Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $11–17
- Website
- Greyhound
Bus from Jacksonville to Mobile Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from La Grange Bus Station to Mobile
- Ave. Duration
- 3h 32m
- Frequency
- Once daily
- Estimated price
- $65–85
- Schedules at
- Omnibus Express
Bus from Loxley to Crestview
- Ave. Duration
- 1h 24m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- Omnibus Express
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- Omnibus Express
- Phone
- 843-757-5782
- Website
- Palmetto Breeze Transit
Bus from Sonic at Walmart to Bluffton Transfer Center
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Schedules at
- Palmetto Breeze Transit
- Ave. Duration
- 49 min
- Estimated price
- $80–180
Veteran's Cab Company
- Phone
- +1-803-327-4131
- Website
- rockhillcabs.com
Veteran's Cab Company
- Phone
- +1-803-327-4131
- Website
- rockhillcabs.com
Emerald Taxi
- Phone
- +1 850-792-2546
- Website
- emeraldtaxiandshuttle.com
H2O Shuttle Taxi and Limo
- Phone
- +1 850-708-2870
Red Cabs of Panama City
- Phone
- +1 850-733-2227
- Website
- myfloridacabs.com
Veteran's Cab Company
- Phone
- +1-803-327-4131
- Website
- rockhillcabs.com
Able Shuttle and Taxi
- Phone
- +1 850-607-0209
Choice Taxi
- Phone
- +1 850-529-1806
- Website
- mychoicetaxi.com
Beeline Transportation
- Phone
- +1 843-683-1139
- Website
- taxihiltonhead.com
Hilton Head Taxi
- Phone
- +1 843-384-6408
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide













