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How to get fromSouth Carolina to Fort Myersby plane, car, bus, taxi, or train

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There are 11 ways to get from South Carolina to Fort Myers by plane, car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Greenville–Spartanburg International Airport to Ft. Myers

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Ft. Myers (RSW)plane plane GSP - RSW
    4h 3m
    $139–603

  2. Line 11 bus to Charleston International Airport, fly to Ft. Myers, line 140 bus

    cheapest
    1. Take the bus from N. Charleston SuperStop on Rivers Ave to Centre Pointe Dr / Tanger Outlet Blvdbus bus
    2. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    3. Take the bus from South Fort Myers Transfer/P&R to Edison Mall Transfer Ctrbus bus
    5h 44m
    $92–449

  3. Drive, bus, taxi, train

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Tampatrain train
    5. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    16h 32m

  4. Drive, bus, taxi, train via Jacksonville

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Jacksonvilletrain train
    5. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus
    6. Take the bus from Wildwood to Fort Myersbus bus
    16h 40m

  5. Drive 530.2 mi

    1. Drive from Charleston to Fort Myerscar car 530.2 mi
    9h 35m
    $97–140

  6. Taxi to Charlotte Douglas International Airport, fly to Ft. Myers

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Ft. Myers (RSW)plane plane CLT - RSW
    4h 27m
    $174–601

  7. Taxi to Asheville Regional Airport, fly to Punta Gorda Airport, taxi

    1. Take the taxi from Greenville to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Punta Gorda Airport (PGD)plane plane AVL - PGD
    3. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    3h 25m
    $283–619

  8. Taxi to Charlotte Douglas International Airport, fly to Sarasota–Bradenton International Airport, bus

    1. Take the taxi from Rock Hill to Charlotte-Airport-CLTtaxi taxi
    2. Fly from Charlotte Douglas International Airport (CLT) to Sarasota–Bradenton International Airport (SRQ)plane plane CLT - SRQ
    3. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    6h 1m
    $204–769

  9. Drive, bus, taxi, train via DeLand

    1. Drive from Charleston to Sonic at Walmartcar car
    2. Take the bus from Sonic at Walmart to Bluffton Transfer Centerbus bus 302
    3. Take the taxi from Bluffton Transfer Center to Savannah Stationtaxi taxi
    4. Take the train from Savannah Station to Delandtrain train
    5. Take the train from DeLand to LYNX Centraltrain train
    6. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    17h 25m

  10. Train, bus

    1. Take the train from Charleston Amtrak Station to Fort Lauderdale Amtrak Stationtrain train Silver Meteor
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus FlixBus 2421
    17h 43m
    $253–496

  11. Train, Amtrak Thruway, bus

    1. Take the train from Charleston Amtrak Station to Orlandotrain train
    2. Take the bus from Orlando, FL to Sarasota Amtrak Bus Stopbus bus
    3. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    18h 52m
    $187–370

South Carolina to Fort Myers by bus and train

Calendar7Weekly Services
Duration18h 52mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Fort Myers.ExpandLaunch map view
  • Distance: 606.9 mi
  • Duration: 4h 3m

What companies run services between South Carolina, USA and Fort Myers, FL, USA?

Breeze Airways, Delta, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Ft. Myers (RSW) every 4 hours.

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