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How to get fromSouth Carolina to Gainesvilleby plane, bus, train (Amtrak), bus (Greyhound), or car

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There are 7 ways to get from South Carolina to Gainesville by plane, bus, train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane GSP - ATL
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    4h 4m
    $122–540

  2. Drive 277.8 mi

    cheapest
    1. Drive from Charleston to Gainesvillecar car 277.8 mi
    6h 5m
    $51–74

  3. Train (Amtrak)

    1. Take the train from Charleston Amtrak Station to Selma Stationtrain train
    2. Take the train from Selma Station to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Gainesville Stationtrain train
    14h 55m
    $216–456

  4. Bus via Charlotte (Greyhound)

    1. Take the bus from Charleston Bus Station to Charlotte Bus Stationbus bus Greyhound US0643S
    2. Take the bus from Charlotte Bus Station to Gainesvillebus bus Greyhound US0670
    15h 2m
    $83–162

  5. Fly from Columbia, bus

    1. Fly from Columbia (CAE) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane CAE - ATL
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    5h 18m
    $72–404

  6. Fly from Charleston International Airport, bus

    1. Fly from Charleston International Airport (CHS) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane CHS - ATL
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    6h 3m
    $355–1,036

  7. Bus

    1. Take the bus from Charleston Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus Charlotte
    17h 28m
    $116–289

Greenville–Spartanburg International Airport (GSP) to Hartsfield-Jackson Atlanta International Airport (ATL) flights

Calendar52Weekly Planes
Duration1h 3mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from South Carolina to Gainesville.ExpandLaunch map view
  • Distance: 232.5 mi
  • Duration: 4h 4m

What companies run services between South Carolina, USA and Gainesville, GA, USA?

You can take a vehicle from Charleston to Gainesville Station via Charleston Amtrak Station, Selma Station, and Charlotte Amtrak Station in around 14h 55m. Alternatively, you can take a bus from Broad St / Meeting St to Gainesville via Spring St / Meeting St, Meeting St / Line St NB, N. Charleston SuperStop, North Charleston Transit Center, Charleston Bus Station, Charlotte Bus Station, and Gainesville in around 15h 2m.

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